MLB Prop Bets: Arizona Diamondbacks vs St. Louis Cardinals (July 18, 2025)

The St. Louis Cardinals (51-46) face the Arizona Diamondbacks (47-50) at Chase Field on Friday at 9:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup.

  • The Cardinals have a 51-42-4 O/U record this season (meaning 51 games have gone over the total runs line, 42 have gone under and four have resulted in a push). The Diamondbacks have a 50-42-5 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.6 runs per game this season (11th in the league). Comparatively, the Diamondbacks are averaging 5.1 (4th).
  • In the field, the Cardinals are allowing 4.4 runs per game this season (20th in the league), while the Diamondbacks are allowing an average of 5.0 runs (26th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .252 (ranking 11th in the Major leagues), while the Diamondbacks are batting .251 (12th).

Home Runs

  • In terms of total home runs this season, the Diamondbacks have hit 141 (4th in the Major Leagues). Meanwhile, the Cardinals have managed 97 (21st).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 423 RBIs to rank 10th in the MLB this season. Comparatively, the Diamondbacks have recorded 482 RBIs to rank 3rd.

Pitching Insights:

Earned Run Average

  • The Diamondbacks have an earned run average of 4.65 this season (26th in the Majors), while The Cardinals have an ERA of 4.11 (20th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 705 this season, ranking 28th in the MLB. Meanwhile, the Diamondbacks rank 12th for total strikeouts, recording 821.

Opponent Batting Average

  • Opponents are batting an average of .252 against the Diamondbacks this season (24th in the Major Leagues). Comparatively, the Cardinals' opponents are at .252 (23rd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 22-29-46 9-19-21 13-10-25 10-13-18 12-16-28 0-0-0 2-5-3
    Diamondbacks 22-29-46 12-13-23 10-16-23 17-15-30 5-14-16 0-0-0 0-4-6

Lead After Three Innings

  • Here are their records after the first three innings in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 35-32-30 15-16-18 20-16-12 20-14-7 15-18-23 0-0-0 3-5-2
    Diamondbacks 41-37-19 21-19-8 20-18-11 31-22-9 10-15-10 0-0-0 4-2-4

NRFI/YRFI

  • The NRFI is 45-52 in Cardinals games this season. The Diamondbacks have a 44-53 NRFI record.

Last Time They Met

The Cardinals recorded a 4-3 victory over the Diamondbacks at Busch Stadium when these teams last met on May 25. Masyn Winn went yard en route to that victory, hitting a home run to go with an RBI. The Cardinals have now won four straight against the Diamondbacks.