MLB Prop Bets: Chicago Cubs vs Philadelphia Phillies (April 21, 2026)
The Philadelphia Phillies (8-14) face the Chicago Cubs (13-9) at Wrigley Field on Tuesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Jesus Luzardo is the probable pitcher for the Phillies, while Shota Imanaga is the probable pitcher for the Cubs. The Cubs are favored to win at -122, while the Phillies are at +102. The total runs line is set at 8.0, with OVER at -117 and UNDER at -103.
- The Phillies (+157) have a 4-18 Run Line record this season, while the Cubs (-191) hold a record of 10-12.
- The Phillies have a 10-11-1 O/U record this season (meaning 10 games have gone over the total runs line, 11 have gone under and one has resulted in a push). The Cubs have a 12-9-1 O/U record.
Scoring Insights
- The Phillies are averaging 3.5 runs per game this season (27th in the league). Comparatively, the Cubs are averaging +1.9 more at 5.3 runs (5th).
- In the field, the Phillies are allowing a whopping 5.4 runs per game this season (28th in the league), while the Cubs are allowing an average of 3.8 runs (8th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Phillies are at .220 (ranking 26th in the Major leagues), while the Cubs are batting .251 (9th).
Home Runs
- In terms of total home runs this season, the Cubs have hit 25 (T8th in the Major Leagues). Meanwhile, the Phillies have managed 22 (T17th).
Runs Batted In
- Finally, looking at their runs batted in, the Phillies have recorded 75 RBIs to rank T25th in the MLB this season. Comparatively, the Cubs have recorded 104 RBIs to rank 8th.
Pitching Insights:
Earned Run Average
- The Cubs have an earned run average of 3.47 this season (9th in the Majors), while The Phillies have an ERA of 4.87 (28th).
Strikeouts
- Turning our attention to total strikeouts, the Phillies have recorded 219 this season, ranking T4th in the MLB. Meanwhile, the Cubs rank 22nd for total strikeouts, recording 182.
Opponent Batting Average
- Opponents are batting an average of only .225 against the Cubs this season (6th in the Major Leagues). Alternatively, the Phillies' opponents are at .275 (30th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 8-6-8 | 6-4-5 | 2-2-3 | 7-5-7 | 1-1-1 | 0-0-0 | 4-2-4 |
| Cubs | 3-4-15 | 2-2-9 | 1-2-6 | 2-2-12 | 1-2-3 | 0-0-0 | 1-3-6 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 8-11-3 | 7-7-1 | 1-4-2 | 7-9-3 | 1-2-0 | 0-0-0 | 5-5-0 |
| Cubs | 10-6-6 | 6-3-4 | 4-3-2 | 8-3-5 | 2-3-1 | 0-0-0 | 3-4-3 |
NRFI/YRFI
The NRFI market is paying -130 and the YRFI is paying +100.
- The NRFI is 8-14 in Phillies games this season. The Cubs have a 15-7 NRFI record.
Last Time They Met
The Cubs recorded a 5-1 victory over the Phillies at Wrigley Field yesterday. The Cubs have now won three straight against the Phillies. Dansby Swanson went yard en route to that victory, hitting a home run to go with 3 RBIs.
