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MLB Prop Bets: Arizona Diamondbacks vs San Diego Padres (April 26, 2026)

The San Diego Padres (18-8) face the Arizona Diamondbacks (14-12) at Estadio Alfredo Harp Helú on Sunday at 4:05pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Michael King is the probable pitcher for the Padres, while Ryne Nelson is the probable pitcher for the Diamondbacks. The Padres are favored to win at -126, while the Diamondbacks are at +104. The total runs line is set at 15.5, with OVER at -108 and UNDER at -112.

  • The Padres (+113) have a 15-11 Run Line record this season, while the Diamondbacks (-136) hold a record of 17-9.
  • The Padres have a 10-15-1 O/U record this season (meaning 10 games have gone over the total runs line, 15 have gone under and one has resulted in a push). The Diamondbacks have a 14-10-2 O/U record.

Scoring Insights

  • The Padres are averaging 4.5 runs per game this season (17th in the league). Comparatively, the Diamondbacks are averaging 4.6 (13th).
  • In the field, the Padres are allowing only 3.8 runs per game this season (4th in the league), while the Diamondbacks are allowing an average of 5.0 runs (T22nd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .233 (ranking 21st in the Major leagues), while the Diamondbacks are batting .249 (11th).

Home Runs

  • In terms of total home runs this season, the Diamondbacks have hit 24 (22nd in the Major Leagues). Meanwhile, the Padres have managed 22 (T23rd).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 111 RBIs to rank T19th in the MLB this season. Comparatively, the Diamondbacks have recorded 114 RBIs to rank 16th.

Pitching Insights:

Earned Run Average

  • The Diamondbacks have an earned run average of 4.44 this season (20th in the Majors), while The Padres have an ERA of 3.63 (7th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 234 this season, ranking T10th in the MLB. Meanwhile, the Diamondbacks rank 28th for total strikeouts, recording 198.

Opponent Batting Average

  • Opponents are batting an average of .250 against the Diamondbacks this season (20th in the Major Leagues). Comparatively, the Padres' opponents are at .239 (15th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 3-4-19 2-3-8 1-1-10 3-2-10 0-2-9 0-0-1 1-1-8
    Diamondbacks 7-7-12 3-4-6 4-3-5 2-2-4 5-5-8 0-0-1 2-3-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 6-11-9 5-5-3 1-5-6 3-5-7 3-6-2 0-1-0 2-5-3
    Diamondbacks 9-10-7 4-4-5 4-6-2 4-1-3 5-9-4 1-0-0 3-3-4

NRFI/YRFI

The NRFI market is paying +190 and the YRFI is paying -250.

  • The NRFI is 19-7 in Padres games this season. The Diamondbacks have a 10-16 NRFI record.

Last Time They Met

The Padres recorded a 6-4 victory over the Diamondbacks at Estadio Alfredo Harp Helú yesterday. Ty France was crushing the ball in that matchup, hitting 2 home runs and recording 2 RBIs. The Padres have now won six straight against the Diamondbacks.