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MLB Prop Bets: Seattle Mariners vs San Diego Padres (May 17, 2026)

The San Diego Padres (27-18) face the Seattle Mariners (22-25) at T-Mobile Park on Sunday at 7:20pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Lucas Giolito is the probable pitcher for the Padres, while George Kirby is the probable pitcher for the Mariners. The Mariners are favored to win at -157, while the Padres are at +130. The total runs line is set at 7.5, with OVER at -108 and UNDER at -112.

  • The Padres (-164) have a 22-23 Run Line record this season, while the Mariners (+136) hold a record of 19-28.
  • The Padres have a 19-25-1 O/U record this season (meaning 19 games have gone over the total runs line, 25 have gone under and one has resulted in a push). The Mariners have a 21-25-1 O/U record.

Scoring Insights

  • The Padres are averaging 4.2 runs per game this season (21st in the league). Comparatively, the Mariners are averaging 4.1 (22nd).
  • In the field, the Padres are allowing 4.1 runs per game this season (9th in the league), while the Mariners are allowing an average of 3.9 runs (6th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .223 (ranking 30th in the Major leagues), while the Mariners are batting .232 (23rd).

Home Runs

  • In terms of total home runs this season, the Mariners have hit 54 (10th in the Major Leagues). Meanwhile, the Padres have managed 44 (T18th).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 180 RBIs to rank T22nd in the MLB this season. Comparatively, the Mariners have recorded 190 RBIs to rank T14th.

Pitching Insights:

Earned Run Average

  • The Mariners have an earned run average of 3.66 this season (7th in the Majors), while The Padres have an ERA of 4.04 (16th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 395 this season, ranking 11th in the MLB. Meanwhile, the Mariners rank 10th for total strikeouts, recording 397.

Opponent Batting Average

  • Opponents are batting an average of .252 against the Mariners this season (24th in the Major Leagues). Comparatively, the Padres' opponents are at .238 (13th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 5-7-33 4-3-16 1-4-15 5-3-18 0-4-15 0-0-2 1-1-8
    Mariners 12-12-23 8-8-9 4-4-14 12-11-19 0-1-4 0-0-0 3-2-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 9-20-16 6-10-7 2-9-9 5-10-11 4-10-5 1-1-0 2-2-6
    Mariners 19-16-12 11-9-5 8-7-7 16-15-11 3-1-1 0-0-0 5-2-3

NRFI/YRFI

  • The NRFI is 33-12 in Padres games this season. The Mariners have a 20-27 NRFI record.

Last Time They Met

The Padres recorded an upset 7-4 victory over the Mariners at T-Mobile Park yesterday. Nick Castellanos went yard en route to that victory, hitting a home run to go with 3 RBIs. The Padres have now won five straight against the Mariners.