MLB Prop Bets: St. Louis Cardinals vs Pittsburgh Pirates (May 19, 2026)
The Pittsburgh Pirates (24-23) face the St. Louis Cardinals (27-19) at Busch Stadium on Tuesday at 7:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Mitch Keller is the probable pitcher for the Pirates, while Matthew Liberatore is the probable pitcher for the Cardinals. The Pirates opened as favorites but this matchup has since become a pick'em, with both the Pirates and Cardinals at -110 to win. The total runs line is set at 8.0, with OVER at -114 and UNDER at -106.
- The Pirates (+149) have a 24-23 Run Line record this season, while the Cardinals (-181) hold a record of 30-16.
- The Pirates have a 24-22-1 O/U record this season (meaning 24 games have gone over the total runs line, 22 have gone under and one has resulted in a push). The Cardinals have a 20-24-2 O/U record.
Scoring Insights
- The Pirates are averaging 4.9 runs per game this season (7th in the league). Comparatively, the Cardinals are averaging 4.5 (11th).
- In the field, the Pirates are allowing 4.5 runs per game this season (19th in the league), while the Cardinals are allowing an average of 4.5 runs (16th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Pirates are at .248 (ranking 6th in the Major leagues), while the Cardinals are batting .241 (15th).
Home Runs
- In terms of total home runs this season, the Cardinals have hit 51 (T13th in the Major Leagues). Meanwhile, the Pirates have managed 49 (17th).
Runs Batted In
- Finally, looking at their runs batted in, the Pirates have recorded 220 RBIs to rank 6th in the MLB this season. Comparatively, the Cardinals have recorded 202 RBIs to rank T13th.
Pitching Insights:
Earned Run Average
- The Cardinals have an earned run average of 4.12 this season (17th in the Majors), while The Pirates have an ERA of 3.88 (11th).
Strikeouts
- Turning our attention to total strikeouts, the Pirates have recorded an impressive 421 this season, ranking T6th in the MLB. Contrastingly, the Cardinals rank 30th for total strikeouts, recording only 330.
Opponent Batting Average
- Opponents are batting an average of .252 against the Cardinals this season (24th in the Major Leagues). Comparatively, the Pirates' opponents are at .226 (6th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Pirates | 16-6-25 | 9-4-13 | 7-2-12 | 11-3-13 | 5-3-12 | 0-0-0 | 3-1-6 |
| Cardinals | 8-9-29 | 3-4-16 | 5-5-13 | 1-3-1 | 7-6-28 | 0-0-0 | 2-3-5 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Pirates | 22-11-14 | 14-5-7 | 8-6-7 | 16-5-6 | 6-6-8 | 0-0-0 | 5-2-3 |
| Cardinals | 18-14-14 | 10-6-7 | 8-8-7 | 2-2-1 | 16-12-13 | 0-0-0 | 2-3-5 |
NRFI/YRFI
The NRFI market is paying -130 and the YRFI is paying +100.
- The NRFI is 24-23 in Pirates games this season. The Cardinals have a 24-22 NRFI record.
Last Time They Met
The Cardinals recorded a 10-5 victory over the Pirates at PNC Park when these teams last met on April 30. Jordan Walker was unstoppable in that matchup, hitting a home run, a single and recording 3 RBIs. The Cardinals have now won five straight against the Pirates.
