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MLB Prop Bets: San Diego Padres vs Athletics (May 24, 2026)

The Athletics (26-26) face the San Diego Padres (31-20) at Petco Park on Sunday at 4:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Luis Medina is the probable pitcher for the Athletics, while Michael King is the probable pitcher for the Padres. The Padres are favored to win at -171, while the Athletics are at +141. The total runs line is set at 8.0, with OVER at -118 and UNDER at -102.

  • The Athletics (-156) have a 28-24 Run Line record this season, while the Padres (+129) hold a record of 27-24.
  • The Athletics have a 24-25-3 O/U record this season (meaning 24 games have gone over the total runs line, 25 have gone under and three have resulted in a push). The Padres have a 22-28-1 O/U record.

Scoring Insights

  • The Athletics are averaging 4.4 runs per game this season (14th in the league). Comparatively, the Padres are averaging 4.1 (20th).
  • In the field, the Athletics are allowing 4.6 runs per game this season (T20th in the league), while the Padres are allowing an average of 3.9 runs (8th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Athletics are at an impressive .248 (ranking 5th in the Major leagues), while the Padres are batting an underwhelming .219 (30th).

Home Runs

  • In terms of total home runs this season, the Padres have hit 52 (T17th in the Major Leagues). Meanwhile, the Athletics have managed 54 (T15th).

Runs Batted In

  • Finally, looking at their runs batted in, the Athletics have recorded 223 RBIs to rank 10th in the MLB this season. Comparatively, the Padres have recorded 202 RBIs to rank 24th.

Pitching Insights:

Earned Run Average

  • The Padres have an earned run average of 3.84 this season (12th in the Majors), while The Athletics have an ERA of 4.29 (23rd).

Strikeouts

  • Turning our attention to total strikeouts, the Athletics have recorded 411 this season, ranking T23rd in the MLB. Meanwhile, the Padres rank 14th for total strikeouts, recording 441.

Opponent Batting Average

  • Opponents are batting an average of .233 against the Padres this season (11th in the Major Leagues). Comparatively, the Athletics' opponents are at .250 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 10-15-27 4-8-10 6-7-17 3-6-8 7-9-19 0-0-0 1-2-7
    Padres 7-8-36 5-4-19 2-4-15 5-3-19 2-5-17 0-0-2 2-2-6

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 21-19-12 8-9-5 13-10-7 4-9-4 17-10-8 0-0-0 3-5-2
    Padres 13-21-17 9-11-8 3-9-9 5-10-12 8-11-5 1-1-0 5-2-3

NRFI/YRFI

The NRFI market is paying -115 and the YRFI is paying -115.

  • The NRFI is 24-28 in Athletics games this season. The Padres have a 34-17 NRFI record.

Last Time They Met

The Padres recorded a 2-0 victory over the Athletics at Petco Park yesterday. Jackson Merrill led the way to that victory, hitting a home run. The Padres have now won five straight at Petco Park against the Athletics.