MLB Prop Bets: St. Louis Cardinals vs San Diego Padres (June 17, 2026)

The San Diego Padres (37-35) face the St. Louis Cardinals (40-31) at Busch Stadium on Wednesday at 2:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Kyle Leahy is the probable pitcher for the Cardinals, while the Padres' probable pitcher remains unclear.

The Padres have a 31-40-1 O/U record this season (meaning 31 games have gone over the total runs line, 40 have gone under and one has resulted in a push). The Cardinals have a 31-37-3 O/U record.

Scoring Insights

The Padres are averaging 3.8 runs per game this season (30th in the league). Comparatively, the Cardinals are averaging +0.8 more at 4.6 runs (11th).
In the field, the Padres are allowing only 4.0 runs per game this season (6th in the league), while the Cardinals are allowing an average of 4.4 runs (14th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

Looking at their batting averages this season, the Padres are at .216 (ranking 30th in the Major leagues), while the Cardinals are batting .246 (11th).

Home Runs

In terms of total home runs this season, the Cardinals have hit 83 (16th in the Major Leagues). Meanwhile, the Padres have managed 73 (T20th).

Runs Batted In

Finally, looking at their runs batted in, the Padres have recorded 267 RBIs to rank 30th in the MLB this season. Comparatively, the Cardinals have recorded 314 RBIs to rank 14th.

Pitching Insights:

Earned Run Average

The Cardinals have an earned run average of 4.06 this season (14th in the Majors), while The Padres have an ERA of 3.89 (8th).

Strikeouts

Turning our attention to total strikeouts, the Padres have recorded 597 this season, ranking 17th in the MLB. Meanwhile, the Cardinals rank 28th for total strikeouts, recording 549.

Opponent Batting Average

Opponents are batting an average of .250 against the Cardinals this season (22nd in the Major Leagues). Comparatively, the Padres' opponents are at .241 (16th).