

MLB Prop Bets: Cleveland Guardians vs Chicago White Sox (October 10, 2026)
The Chicago White Sox face the Cleveland Guardians at Progressive Field in Game 5 of the MLB League Division Round on Saturday at 8:00pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Sean Burke is the probable pitcher for the White Sox, while Gavin Williams is the probable pitcher for the Guardians. The Guardians are favored to win at -137, while the White Sox are at +113. The total runs line is set at 7.0, with OVER at -120 and UNDER at +100.
- The White Sox (-193) have a 94-74 Run Line record since the beginning of the regular season, while the Guardians (+158) hold a record of 79-87.
- The White Sox have a 97-69-2 O/U record since the beginning of the regular season (meaning 97 games have gone over the total runs line, 69 have gone under and two have resulted in a push). The Guardians have an 80-84-2 O/U record.
Scoring Insights
- The White Sox averaged 4.8 runs per game during the regular season (5th in the league). Comparatively, the Guardians averaged 4.2 (24th). During the postseason, the White Sox are averaging 4.7 per game and the Guardians are averaging 5.3.
- In the field, the White Sox allowed 4.4 runs per game during the regular season (15th in the league), while the Guardians allowed an average of 4.1 runs (8th). More recently, the White Sox are allowing 4.5 per game in these playoffs, while the Guardians are allowing an average of 3.8.
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages during the regular season, the White Sox were at .236 (ranking 25th in the Major leagues), while the Guardians were batting .239 (24th). During the playoffs, the White Sox are at .228 and the Guardians are batting .214.
Home Runs
- In terms of total home runs during the regular season, the Guardians hit 162 (27th in the Major Leagues). Meanwhile, the White Sox managed 211 (5th). The postseason has thus far seen the White Sox hit 4 home runs, while the Guardians have hit 2.
Runs Batted In
- Finally, looking at their runs batted in, the White Sox recorded 740 RBIs to rank 5th in the MLB during the regular season. Comparatively, the Guardians recorded 650 RBIs to rank 24th. The White Sox have recorded 26 RBIs in the playoffs, while the Guardians have recorded 20.
Pitching Insights:
Earned Run Average
- The Guardians had an earned run average of 3.77 during the regular season (8th in the Majors), while The White Sox had an ERA of 4.12 (15th). In the playoffs, the White Sox have an ERA of 4.17, while the Guardians have an ERA of 3.75.
Strikeouts
- Turning our attention to total strikeouts, the White Sox recorded 1337 in the regular season season, ranking T16th in the MLB. Meanwhile, the Guardians ranked 3rd for total strikeouts, recording 1530. The White Sox have recorded 52 strikeouts during the postseason and the Guardians have managed 54.
Opponent Batting Average
- Opponents batted an average of .238 against the Guardians in the regular season (11th in the Major Leagues). Comparatively, the White Sox's opponents were at .243 (17th). Throughout these playoffs, the White Sox's opponents are batting an average of .199 and the Guardians' opponents are batting an average of .205.
First Innings Moneyline
- Here are their first innings moneyline records in 2026 (including playoffs).
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| White Sox | 45-43-80 | 24-19-40 | 21-24-40 | 16-8-30 | 29-35-50 | 0-0-0 | 5-2-3 |
| Guardians | 38-30-98 | 22-14-47 | 16-16-51 | 27-19-59 | 11-11-39 | 0-0-0 | 2-3-5 |
Lead After Three Innings
The White Sox are +110 to lead after three innings, while the Guardians are -140.
- Here are their records after the first three innings in 2026 (including playoffs).
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| White Sox | 63-58-47 | 34-25-24 | 29-33-23 | 22-11-21 | 41-47-26 | 0-0-0 | 6-3-1 |
| Guardians | 61-53-52 | 36-25-22 | 25-28-30 | 41-34-30 | 20-19-22 | 0-0-0 | 5-1-4 |
NRFI/YRFI
The NRFI market is paying -170 and the YRFI is paying +130.
- The NRFI is 74-94 in White Sox games since the beginning of the regular season. The Guardians have a 92-74 NRFI record. Drilling down further, the NRFI is 2-4 in White Sox playoff games this season and 2-2 in Guardians playoff games this season.
Last Time They Met
The Guardians recorded a 9-5 victory over the White Sox at Rate Field on Thursday. Despite being on the wrong side of that result, Miguel Vargas did what he could, hitting a home run. The series is tied at 2-2