MLB Prop Bets: St. Louis Cardinals vs Cleveland Guardians (April 14, 2026)
The Cleveland Guardians (10-7) face the St. Louis Cardinals (8-8) at Busch Stadium on Tuesday at 7:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Joey Cantillo is the probable pitcher for the Guardians, while Michael McGreevy is the probable pitcher for the Cardinals. The Guardians are favored to win at -131, while the Cardinals are at +109. The total runs line is set at 9.0, with OVER at -105 and UNDER at -115.
- The Guardians (+129) have a 10-7 Run Line record this season, while the Cardinals (-156) hold a record of 8-8.
- The Guardians have an 8-9-0 O/U record this season (meaning eight games have gone over the total runs line and nine have gone under). The Cardinals have a 9-7-0 O/U record.
Scoring Insights
- The Guardians are averaging 3.9 runs per game this season (24th in the league). Comparatively, the Cardinals are averaging 4.3 (T15th).
- In the field, the Guardians are allowing 4.1 runs per game this season (11th in the league), while the Cardinals are allowing an average of 5.6 runs (28th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Guardians are at .227 (ranking T22nd in the Major leagues), while the Cardinals are batting .226 (24th).
Home Runs
- In terms of total home runs this season, the Cardinals have hit 17 (T10th in the Major Leagues). Meanwhile, the Guardians have managed 17 (T10th).
Runs Batted In
- Finally, looking at their runs batted in, the Guardians have recorded 62 RBIs to rank 24th in the MLB this season. Comparatively, the Cardinals have recorded 68 RBIs to rank T13th.
Pitching Insights:
Earned Run Average
- The Cardinals have an earned run average of 5.09 this season (28th in the Majors), while The Guardians have an ERA of 3.99 (14th).
Strikeouts
- Turning our attention to total strikeouts, the Guardians have recorded an impressive 166 this season, ranking 2nd in the MLB. Contrastingly, the Cardinals rank 30th for total strikeouts, recording only 97.
Opponent Batting Average
- Opponents are batting an average of .266 against the Cardinals this season (29th in the Major Leagues). Comparatively, the Guardians' opponents are at .232 (15th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Guardians | 3-0-14 | 1-0-5 | 2-0-9 | 0-0-3 | 3-0-11 | 0-0-0 | 2-0-8 |
| Cardinals | 2-3-11 | 1-1-8 | 1-2-3 | 0-1-1 | 2-2-10 | 0-0-0 | 1-3-6 |
Lead After Three Innings
The Guardians are -130 to lead after three innings, while the Cardinals are +100.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Guardians | 6-7-4 | 2-3-1 | 4-4-3 | 1-1-1 | 5-6-3 | 0-0-0 | 3-5-2 |
| Cardinals | 5-5-6 | 4-2-4 | 1-3-2 | 1-1-0 | 4-4-6 | 0-0-0 | 2-4-4 |
NRFI/YRFI
The NRFI market is paying -115 and the YRFI is paying -115.
- The NRFI is 12-5 in Guardians games this season. The Cardinals have a 9-7 NRFI record.
Last Time They Met
The Guardians recorded a 9-3 victory over the Cardinals at Busch Stadium yesterday. Brayan Rocchio was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs. That result snapped the Cardinals' five-game winning streak against the Guardians.
