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MLB Prop Bets: Cleveland Guardians vs Baltimore Orioles (April 16, 2026)

The Baltimore Orioles (9-9) face the Cleveland Guardians (10-9) at Progressive Field on Thursday at 6:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Shane Baz is the probable pitcher for the Orioles, while Parker Messick is the probable pitcher for the Guardians. The Guardians are favored to win at -122, while the Orioles are at +102. The total runs line is set at 8.0, with OVER at -108 and UNDER at -112.

  • The Orioles (+159) have a 7-11 Run Line record this season, while the Guardians (-193) hold a record of 10-9.
  • The Orioles have a 9-9-0 O/U record this season (meaning nine games have gone over the total runs line and nine have gone under). The Guardians have a 9-10-0 O/U record.

Scoring Insights

  • The Orioles are averaging 4.3 runs per game this season (T16th in the league). Comparatively, the Guardians are averaging 3.9 (24th).
  • In the field, the Orioles are allowing 4.3 runs per game this season (14th in the league), while the Guardians are allowing an average of 4.3 runs (13th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Orioles are at .245 (ranking 8th in the Major leagues), while the Guardians are batting .229 (20th).

Home Runs

  • In terms of total home runs this season, the Guardians have hit 19 (T13th in the Major Leagues). Meanwhile, the Orioles have managed 17 (T17th).

Runs Batted In

  • Finally, looking at their runs batted in, the Orioles have recorded 76 RBIs to rank 15th in the MLB this season. Comparatively, the Guardians have recorded 70 RBIs to rank T21st.

Pitching Insights:

Earned Run Average

  • The Guardians have an earned run average of 4.06 this season (15th in the Majors), while The Orioles have an ERA of 3.99 (14th).

Strikeouts

  • Turning our attention to total strikeouts, the Orioles have recorded 159 this season, ranking T12th in the MLB. Meanwhile, the Guardians rank 4th for total strikeouts, recording 181.

Opponent Batting Average

  • Opponents are batting an average of .236 against the Guardians this season (18th in the Major Leagues). Comparatively, the Orioles' opponents are at .253 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Orioles 1-2-15 1-1-10 0-1-5 1-1-13 0-1-2 0-0-0 1-2-7
    Guardians 4-0-15 1-0-5 3-0-10 0-0-4 4-0-11 0-0-0 3-0-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Orioles 5-8-5 5-5-2 0-3-3 4-6-5 1-2-0 0-0-0 3-4-3
    Guardians 6-7-6 2-3-1 4-4-5 1-1-2 5-6-4 0-0-0 3-4-3

NRFI/YRFI

The NRFI market is paying -145 and the YRFI is paying +110.

  • The NRFI is 14-4 in Orioles games this season. The Guardians have a 12-7 NRFI record.

Last Time They Met

The Orioles recorded a 4-3 victory over the Guardians at Progressive Field when these teams last met on July 24, 2025. Steven Kwan was crushing the ball in that matchup, hitting 2 home runs and recording 2 RBIs. That result snapped the Guardians' three-game winning streak against the Orioles.