MLB Prop Bets: Houston Astros vs St. Louis Cardinals (April 17, 2026)
The St. Louis Cardinals (10-8) face the Houston Astros (8-12) at Daikin Park on Friday at 8:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Kyle Leahy is the probable pitcher for the Cardinals, while the Astros' probable pitcher remains unclear.
- The Cardinals have a 10-8-0 O/U record this season (meaning 10 games have gone over the total runs line and eight have gone under). The Astros have a 13-7-0 O/U record.
Scoring Insights
- The Cardinals are averaging 4.4 runs per game this season (14th in the league). Comparatively, the Astros are averaging 5.3 (5th).
- In the field, the Cardinals are allowing a whopping 5.4 runs per game this season (T27th in the league), while the Astros are allowing an average of 5.8 runs (29th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cardinals are at .231 (ranking 22nd in the Major leagues), while the Astros are batting .264 (4th).
Home Runs
- In terms of total home runs this season, the Astros have hit 21 (T7th in the Major Leagues). Meanwhile, the Cardinals have managed 20 (T10th).
Runs Batted In
- Finally, looking at their runs batted in, the Cardinals have recorded 79 RBIs to rank T15th in the MLB this season. Comparatively, the Astros have recorded 99 RBIs to rank 4th.
Pitching Insights:
Earned Run Average
- The Astros have an earned run average of 6.01 this season (30th in the Majors), while The Cardinals have an ERA of 4.94 (27th).
Strikeouts
- Turning our attention to total strikeouts, the Astros have recorded an impressive 189 this season, ranking 3rd in the MLB. Contrastingly, the Cardinals rank 30th for total strikeouts, recording only 111.
Opponent Batting Average
- Opponents are batting an average of .265 against the Astros this season (29th in the Major Leagues). Comparatively, the Cardinals' opponents are at .264 (27th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 2-4-12 | 1-2-9 | 1-2-3 | 0-2-1 | 2-2-11 | 0-0-0 | 1-3-6 |
| Astros | 7-6-7 | 5-1-4 | 2-5-3 | 4-2-7 | 3-4-0 | 0-0-0 | 3-6-1 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 5-5-8 | 4-2-6 | 1-3-2 | 1-1-1 | 4-4-7 | 0-0-0 | 2-3-5 |
| Astros | 8-6-6 | 5-2-3 | 3-4-3 | 5-4-4 | 3-2-2 | 0-0-0 | 5-3-2 |
NRFI/YRFI
- The NRFI is 9-9 in Cardinals games this season. The Astros have a 6-14 NRFI record.
Last Time They Met
The Cardinals recorded a 4-1 victory over the Astros at Busch Stadium when these teams last met on April 16, 2025. Lars Nootbaar went yard en route to that victory, hitting a home run to go with 3 RBIs.
