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MLB Prop Bets: Minnesota Twins vs Houston Astros (May 19, 2026)

The Houston Astros (19-30) face the Minnesota Twins (22-26) at Target Field on Tuesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Lance McCullers Jr. is the probable pitcher for the Astros, while Zebby Matthews is the probable pitcher for the Twins. The Twins are favored to win at -143, while the Astros are at +119. The total runs line is set at 8.5, with OVER at -106 and UNDER at -113.

  • The Astros (-175) have a 19-30 Run Line record this season, while the Twins (+144) hold a record of 25-23.
  • The Astros have a 28-18-3 O/U record this season (meaning 28 games have gone over the total runs line, 18 have gone under and three have resulted in a push). The Twins have a 27-17-4 O/U record.

Scoring Insights

  • The Astros are averaging 4.4 runs per game this season (16th in the league). Comparatively, the Twins are averaging 4.7 (9th).
  • In the field, the Astros are allowing a whopping 5.5 runs per game this season (28th in the league), while the Twins are allowing an average of 4.8 runs (23rd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Astros are at .250 (ranking 4th in the Major leagues), while the Twins are batting .236 (19th).

Home Runs

  • In terms of total home runs this season, the Twins have hit 53 (T11th in the Major Leagues). Meanwhile, the Astros have managed 59 (T6th).

Runs Batted In

  • Finally, looking at their runs batted in, the Astros have recorded 205 RBIs to rank 12th in the MLB this season. Comparatively, the Twins have recorded 212 RBIs to rank 8th.

Pitching Insights:

Earned Run Average

  • The Twins have an earned run average of 4.32 this season (22nd in the Majors), while The Astros have an ERA of 5.45 (30th).

Strikeouts

  • Turning our attention to total strikeouts, the Astros have recorded 420 this season, ranking 9th in the MLB. Meanwhile, the Twins rank 26th for total strikeouts, recording 360.

Opponent Batting Average

  • Opponents are batting an average of .246 against the Twins this season (20th in the Major Leagues). Comparatively, the Astros' opponents are at .257 (26th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 16-13-20 10-6-10 6-7-10 4-4-8 12-9-12 0-0-0 1-2-7
    Twins 11-10-27 9-3-15 2-7-12 2-2-5 9-8-22 0-0-0 2-3-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 17-18-14 10-10-6 7-8-8 6-6-4 11-12-10 0-0-0 2-4-4
    Twins 22-15-11 14-6-7 8-9-4 6-2-1 16-13-10 0-0-0 5-3-2

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -110.

  • The NRFI is 19-30 in Astros games this season. The Twins have a 27-21 NRFI record.

Last Time They Met

The Twins recorded a 6-3 victory over the Astros at Target Field yesterday. Josh Bell was crushing the ball in that matchup, hitting 2 home runs and recording 4 RBIs. That result snapped the Astros' four-game winning streak against the Twins.