home team icon
away team icon

MLB Prop Bets: Cleveland Guardians vs Washington Nationals (May 25, 2026)

The Washington Nationals (27-27) face the Cleveland Guardians (32-23) at Progressive Field on Monday at 6:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Zack Littell is the probable pitcher for the Nationals, while Tanner Bibee is the probable pitcher for the Guardians. The Guardians are favored to win at -181, while the Nationals are at +149. The total runs line is set at 8.0, with OVER at -114 and UNDER at -106.

  • The Nationals (-148) have a 34-20 Run Line record this season, while the Guardians (+122) hold a record of 29-26.
  • The Nationals have a 33-19-2 O/U record this season (meaning 33 games have gone over the total runs line, 19 have gone under and two have resulted in a push). The Guardians have a 26-29-0 O/U record.

Scoring Insights

  • The Nationals are averaging 5.3 runs per game this season (1st in the league). Comparatively, the Guardians are averaging only 4.2 (18th).
  • In the field, the Nationals are allowing a whopping 5.6 runs per game this season (30th in the league), while the Guardians are allowing an average of 3.8 runs (6th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Nationals are at .243 (ranking 11th in the Major leagues), while the Guardians are batting .228 (25th).

Home Runs

  • In terms of total home runs this season, the Guardians have hit 55 (T15th in the Major Leagues). Meanwhile, the Nationals have managed 65 (7th).

Runs Batted In

  • Finally, looking at their runs batted in, the Nationals have recorded 270 RBIs to rank 2nd in the MLB this season. Comparatively, the Guardians have recorded 222 RBIs to rank T15th.

Pitching Insights:

Earned Run Average

  • The Guardians have one of the strongest earned run averages this season, sitting at 3.55 (6th in the Majors), while the Nationals are at the opposite end of the scale with an ERA of 4.80 (26th).

Strikeouts

  • Turning our attention to total strikeouts, the Nationals have recorded 431 this season, ranking 19th in the MLB. Meanwhile, the Guardians rank 1st for total strikeouts, recording 515.

Opponent Batting Average

  • Opponents are batting an average of .231 against the Guardians this season (9th in the Major Leagues). Comparatively, the Nationals' opponents are at .254 (27th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Nationals 16-11-27 9-6-11 7-5-16 0-1-2 16-10-25 0-0-0 1-2-7
    Guardians 11-8-36 6-3-16 5-5-20 6-5-19 5-3-17 0-0-0 1-1-8

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Nationals 18-22-14 10-11-5 8-11-9 1-0-2 17-22-12 0-0-0 4-2-4
    Guardians 22-16-17 12-6-7 10-10-10 12-7-11 10-9-6 0-0-0 4-2-4

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -110.

  • The NRFI is 27-27 in Nationals games this season. The Guardians have a 33-22 NRFI record.

Last Time They Met

The Guardians recorded an 8-6 victory over the Nationals at Nationals Park when these teams last met on May 7, 2025. Despite being on the wrong side of that result, Amed Rosario went yard in that matchup, hitting a home run to go with 2 RBIs.