MLB Prop Bets: San Diego Padres vs Philadelphia Phillies (May 25, 2026)
The Philadelphia Phillies (26-27) face the San Diego Padres (31-21) at Petco Park on Monday at 6:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Jesus Luzardo is the probable pitcher for the Phillies, while Randy Vasquez is the probable pitcher for the Padres. The Phillies are favored to win at -131, while the Padres are at +108. The total runs line is set at 7.5, with OVER at -102 and UNDER at -118.
- The Phillies (+130) have a 17-36 Run Line record this season, while the Padres (-157) hold a record of 27-25.
- The Phillies have a 24-27-2 O/U record this season (meaning 24 games have gone over the total runs line, 27 have gone under and two have resulted in a push). The Padres have a 22-29-1 O/U record.
Scoring Insights
- The Phillies are averaging 4.0 runs per game this season (23rd in the league). Comparatively, the Padres are averaging 4.1 (19th).
- In the field, the Phillies are allowing 4.5 runs per game this season (18th in the league), while the Padres are allowing an average of 3.9 runs (9th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Phillies are at .229 (ranking 24th in the Major leagues), while the Padres are batting .220 (30th).
Home Runs
- In terms of total home runs this season, the Padres have hit 53 (18th in the Major Leagues). Meanwhile, the Phillies have managed 62 (9th).
Runs Batted In
- Finally, looking at their runs batted in, the Phillies have recorded 209 RBIs to rank T21st in the MLB this season. Comparatively, the Padres have recorded 204 RBIs to rank 24th.
Pitching Insights:
Earned Run Average
- The Padres have an earned run average of 3.86 this season (13th in the Majors), while The Phillies have an ERA of 4.14 (17th).
Strikeouts
- Turning our attention to total strikeouts, the Phillies have recorded 498 this season, ranking 2nd in the MLB. Meanwhile, the Padres rank 13th for total strikeouts, recording 452.
Opponent Batting Average
- Opponents are batting an average of .234 against the Padres this season (11th in the Major Leagues). Comparatively, the Phillies' opponents are at .262 (29th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 16-12-25 | 10-7-13 | 6-5-12 | 14-9-15 | 2-3-10 | 0-0-0 | 3-0-7 |
| Padres | 7-9-36 | 5-5-19 | 2-4-15 | 5-4-19 | 2-5-17 | 0-0-2 | 2-3-5 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 18-22-13 | 12-12-6 | 6-10-7 | 15-16-7 | 3-6-6 | 0-0-0 | 2-2-6 |
| Padres | 13-22-17 | 9-12-8 | 3-9-9 | 5-11-12 | 8-11-5 | 1-1-0 | 5-3-2 |
NRFI/YRFI
The NRFI market is paying -120 and the YRFI is paying -105.
- The NRFI is 25-28 in Phillies games this season. The Padres have a 34-18 NRFI record.
Last Time They Met
The Phillies recorded a 2-1 victory over the Padres at Petco Park when these teams last met on July 13, 2025. Despite being on the wrong side of that result, Xander Bogaerts did what he could, hitting a home run.
