

MLB Prop Bets: St. Louis Cardinals vs Arizona Diamondbacks (June 25, 2026)
The Arizona Diamondbacks (41-39) face the St. Louis Cardinals (42-36) at Busch Stadium on Thursday at 7:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Zac Gallen is the probable pitcher for the Diamondbacks, while Michael McGreevy is the probable pitcher for the Cardinals. The Cardinals are favored to win at -136, while the Diamondbacks are at +113. The total runs line is set at 9.0, with OVER at -102 and UNDER at -118.
- The Diamondbacks (-188) have a 46-34 Run Line record this season, while the Cardinals (+154) hold a record of 46-32.
- The Diamondbacks have a 32-41-7 O/U record this season (meaning 32 games have gone over the total runs line, 41 have gone under and seven have resulted in a push). The Cardinals have a 35-40-3 O/U record.
Scoring Insights
- The Diamondbacks are averaging 4.3 runs per game this season (18th in the league). Comparatively, the Cardinals are averaging 4.6 (11th).
- In the field, the Diamondbacks are allowing 4.6 runs per game this season (16th in the league), while the Cardinals are allowing an average of 4.6 runs (17th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Diamondbacks are at .239 (ranking 22nd in the Major leagues), while the Cardinals are batting .249 (9th).
Home Runs
- In terms of total home runs this season, the Cardinals have hit 88 (17th in the Major Leagues). Meanwhile, the Diamondbacks have managed 71 (27th).
Runs Batted In
- Finally, looking at their runs batted in, the Diamondbacks have recorded 333 RBIs to rank 18th in the MLB this season. Comparatively, the Cardinals have recorded 347 RBIs to rank 15th.
Pitching Insights:
Earned Run Average
- The Cardinals have an earned run average of 4.30 this season (19th in the Majors), while The Diamondbacks have an ERA of 4.29 (17th).
Strikeouts
- Turning our attention to total strikeouts, the Diamondbacks have recorded 556 this season, ranking 30th in the MLB. Meanwhile, the Cardinals rank 28th for total strikeouts, recording 587.
Opponent Batting Average
- Opponents are batting an average of .256 against the Cardinals this season (24th in the Major Leagues). Comparatively, the Diamondbacks' opponents are at .251 (22nd).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Diamondbacks | 15-22-43 | 8-10-21 | 7-12-20 | 9-8-18 | 6-14-25 | 0-0-2 | 0-3-7 |
| Cardinals | 15-14-49 | 5-7-29 | 10-7-20 | 6-5-12 | 9-9-37 | 0-0-0 | 3-1-6 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Diamondbacks | 25-40-15 | 15-14-10 | 9-25-5 | 16-10-9 | 9-30-6 | 1-1-0 | 2-6-2 |
| Cardinals | 34-20-24 | 17-10-14 | 17-10-10 | 12-5-6 | 22-15-18 | 0-0-0 | 5-2-3 |
NRFI/YRFI
The NRFI market is paying -110 and the YRFI is paying -120.
- The NRFI is 37-43 in Diamondbacks games this season. The Cardinals have a 42-36 NRFI record.
Last Time They Met
The Diamondbacks recorded a 9-4 victory over the Cardinals at Busch Stadium yesterday. Jose Fermin was unstoppable in that matchup, hitting a home run, a single and recording an RBI.











