

MLB Prop Bets: St. Louis Cardinals vs Arizona Diamondbacks (July 23, 2026)
The Arizona Diamondbacks (53-49) face the St. Louis Cardinals (52-49) at Busch Stadium on Thursday at 5:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Brandon Pfaadt is the probable pitcher for the Diamondbacks, while Michael McGreevy is the probable pitcher for the Cardinals. The Cardinals are favored to win at -123, while the Diamondbacks are at +102. The total runs line is set at 8.0, with OVER at -105 and UNDER at -115.
- The Diamondbacks (-198) have a 56-46 Run Line record this season, while the Cardinals (+162) hold a record of 58-43.
- The Diamondbacks have a 41-52-9 O/U record this season (meaning 41 games have gone over the total runs line, 52 have gone under and nine have resulted in a push). The Cardinals have a 41-56-4 O/U record.
Scoring Insights
- The Diamondbacks are averaging 4.5 runs per game this season (15th in the league). Comparatively, the Cardinals are averaging 4.4 (17th).
- In the field, the Diamondbacks are allowing 4.5 runs per game this season (17th in the league), while the Cardinals are allowing an average of 4.4 runs (13th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Diamondbacks are at .240 (ranking 19th in the Major leagues), while the Cardinals are batting .240 (18th).
Home Runs
- In terms of total home runs this season, the Cardinals have hit 110 (22nd in the Major Leagues). Meanwhile, the Diamondbacks have managed 100 (28th).
Runs Batted In
- Finally, looking at their runs batted in, the Diamondbacks have recorded 434 RBIs to rank T16th in the MLB this season. Comparatively, the Cardinals have recorded 436 RBIs to rank 15th.
Pitching Insights:
Earned Run Average
- The Cardinals have an earned run average of 4.12 this season (12th in the Majors), while The Diamondbacks have an ERA of 4.21 (15th).
Strikeouts
- Turning our attention to total strikeouts, the Diamondbacks have recorded 695 this season, ranking 30th in the MLB. Meanwhile, the Cardinals rank 28th for total strikeouts, recording 764.
Opponent Batting Average
- Opponents are batting an average of .251 against the Cardinals this season (22nd in the Major Leagues). Comparatively, the Diamondbacks' opponents are at .252 (24th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Diamondbacks | 22-27-53 | 13-11-27 | 9-16-24 | 12-9-23 | 10-18-30 | 0-0-2 | 1-2-7 |
| Cardinals | 21-18-62 | 9-8-35 | 12-10-27 | 8-6-15 | 13-12-47 | 0-0-0 | 3-1-6 |
Lead After Three Innings
The Diamondbacks are -110 to lead after three innings, while the Cardinals are -120.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Diamondbacks | 32-48-22 | 21-17-13 | 10-30-9 | 20-13-11 | 12-35-11 | 1-1-0 | 2-5-3 |
| Cardinals | 43-29-29 | 22-13-17 | 21-16-12 | 15-7-7 | 28-22-22 | 0-0-0 | 3-3-4 |
NRFI/YRFI
The NRFI market is paying -115 and the YRFI is paying -115.
- The NRFI is 45-57 in Diamondbacks games this season. The Cardinals have a 54-47 NRFI record.
Last Time They Met
The Diamondbacks recorded an 8-7 extra innings victory over the Cardinals at Chase Field on Sunday. Despite being on the wrong side of that result, Blaze Jordan went yard in that matchup, hitting a home run to go with 3 RBIs.

