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MLB Prop Bets: Chicago White Sox vs Houston Astros (July 25, 2026)

The Houston Astros (51-54) face the Chicago White Sox (54-48) at Rate Field on Saturday at 7:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Hunter Brown is the probable pitcher for the Astros, while Sean Burke is the probable pitcher for the White Sox. The White Sox are favored to win at -126, while the Astros are at +105. The total runs line is set at 8.0, with OVER at -117 and UNDER at -103.

  • The Astros (-193) have a 53-52 Run Line record this season, while the White Sox (+158) hold a record of 58-44.
  • The Astros have a 54-45-6 O/U record this season (meaning 54 games have gone over the total runs line, 45 have gone under and six have resulted in a push). The White Sox have a 58-42-2 O/U record.

Scoring Insights

  • The Astros are averaging 4.6 runs per game this season (12th in the league). Comparatively, the White Sox are averaging 4.8 (7th).
  • In the field, the Astros are allowing a whopping 5.0 runs per game this season (25th in the league), while the White Sox are allowing an average of 4.4 runs (11th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Astros are at .243 (ranking 16th in the Major leagues), while the White Sox are batting .240 (19th).

Home Runs

  • In terms of total home runs this season, the White Sox have hit 131 (9th in the Major Leagues). Meanwhile, the Astros have managed 143 (3rd).

Runs Batted In

  • Finally, looking at their runs batted in, the Astros have recorded 461 RBIs to rank 10th in the MLB this season. Comparatively, the White Sox have recorded 468 RBIs to rank 9th.

Pitching Insights:

Earned Run Average

  • The White Sox have an earned run average of 4.13 this season (11th in the Majors), while The Astros have an ERA of 4.71 (26th).

Strikeouts

  • Turning our attention to total strikeouts, the Astros have recorded 923 this season, ranking T7th in the MLB. Meanwhile, the White Sox rank 19th for total strikeouts, recording 862.

Opponent Batting Average

  • Opponents are batting an average of .239 against the White Sox this season (14th in the Major Leagues). Comparatively, the Astros' opponents are at .240 (15th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 32-27-46 18-12-23 14-15-23 11-10-18 21-17-28 0-0-0 3-2-5
    White Sox 26-26-50 13-11-25 13-15-25 5-3-16 21-23-34 0-0-0 2-2-6

Lead After Three Innings

The Astros are +100 to lead after three innings, while the White Sox are -130.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 36-44-25 21-20-12 15-24-13 14-18-7 22-26-18 0-0-0 5-4-1
    White Sox 38-34-30 19-15-15 19-19-15 8-5-11 30-29-19 0-0-0 3-2-5

NRFI/YRFI

The NRFI market is paying -115 and the YRFI is paying -115.

  • The NRFI is 43-62 in Astros games this season. The White Sox have a 47-55 NRFI record.

Last Time They Met

The Astros recorded a 9-5 victory over the White Sox at Rate Field yesterday. Cam Smith went yard en route to that victory, hitting a home run to go with 2 RBIs. The Astros have now won three straight against the White Sox.