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MLB Prop Bets: St. Louis Cardinals vs Cincinnati Reds (July 25, 2026)

The Cincinnati Reds (48-54) face the St. Louis Cardinals (52-51) at Busch Stadium on Saturday at 7:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Hunter Greene is the probable pitcher for the Reds, while Andre Pallante is the probable pitcher for the Cardinals. The Cardinals are favored to win at -123, while the Reds are at +102. The total runs line is set at 8.5, with OVER at -103 and UNDER at -117.

  • The Reds (+165) have a 56-46 Run Line record this season, while the Cardinals (-202) hold a record of 58-45.
  • The Reds have a 56-46-0 O/U record this season (meaning 56 games have gone over the total runs line and 46 have gone under). The Cardinals have a 42-57-4 O/U record.

Scoring Insights

  • The Reds are averaging 4.2 runs per game this season (24th in the league). Comparatively, the Cardinals are averaging 4.4 (16th).
  • In the field, the Reds are allowing 4.8 runs per game this season (23rd in the league), while the Cardinals are allowing an average of 4.5 runs (16th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Reds are at .230 (ranking 28th in the Major leagues), while the Cardinals are batting .240 (21st).

Home Runs

  • In terms of total home runs this season, the Cardinals have hit 110 (22nd in the Major Leagues). Meanwhile, the Reds have managed 135 (T5th).

Runs Batted In

  • Finally, looking at their runs batted in, the Reds have recorded 408 RBIs to rank T25th in the MLB this season. Comparatively, the Cardinals have recorded 444 RBIs to rank 15th.

Pitching Insights:

Earned Run Average

  • The Cardinals have an earned run average of 4.17 this season (13th in the Majors), while The Reds have an ERA of 4.53 (23rd).

Strikeouts

  • Turning our attention to total strikeouts, the Reds have recorded 824 this season, ranking T21st in the MLB. Meanwhile, the Cardinals rank 28th for total strikeouts, recording 781.

Opponent Batting Average

  • Opponents are batting an average of .253 against the Cardinals this season (24th in the Major Leagues). Comparatively, the Reds' opponents are at .246 (19th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Reds 22-27-53 9-12-29 13-15-24 9-6-16 13-21-37 0-0-0 3-2-5
    Cardinals 22-18-63 10-8-36 12-10-27 9-6-16 13-12-47 0-0-0 4-1-5

Lead After Three Innings

The Reds are -115 to lead after three innings, while the Cardinals are -115.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Reds 32-40-30 15-19-16 17-21-14 12-10-9 20-30-21 0-0-0 4-2-4
    Cardinals 44-29-30 23-13-18 21-16-12 16-7-8 28-22-22 0-0-0 4-2-4

NRFI/YRFI

The NRFI market is paying -115 and the YRFI is paying -115.

  • The NRFI is 51-51 in Reds games this season. The Cardinals have a 55-48 NRFI record.

Last Time They Met

The Reds recorded a 4-2 victory over the Cardinals at Busch Stadium yesterday. Eugenio Suarez was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs. That result snapped the Cardinals' three-game winning streak against the Reds.