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MLB Prop Bets: New York Yankees vs St. Louis Cardinals (August 5, 2026)

The St. Louis Cardinals (56-58) face the New York Yankees (64-50) at Yankee Stadium on Wednesday at 7:05pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Andre Pallante is the probable pitcher for the Cardinals, while Will Warren is the probable pitcher for the Yankees. The Yankees are favored to win at -156, while the Cardinals are at +129. The total runs line is set at 8.5, with OVER at -123 and UNDER at +102.

  • The Cardinals (-163) have a 61-53 Run Line record this season, while the Yankees (+135) hold a record of 58-56.
  • The Cardinals have a 45-65-4 O/U record this season (meaning 45 games have gone over the total runs line, 65 have gone under and four have resulted in a push). The Yankees have a 48-61-5 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.4 runs per game this season (19th in the league). Comparatively, the Yankees are averaging 4.6 (11th).
  • In the field, the Cardinals are allowing 4.5 runs per game this season (16th in the league), while the Yankees are allowing an average of 3.8 runs (4th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .239 (ranking 20th in the Major leagues), while the Yankees are batting .232 (27th).

Home Runs

  • In terms of total home runs this season, the Yankees have hit 164 (2nd in the Major Leagues). Meanwhile, the Cardinals have managed 118 (T21st).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 483 RBIs to rank 16th in the MLB this season. Comparatively, the Yankees have recorded 496 RBIs to rank 11th.

Pitching Insights:

Earned Run Average

  • The Yankees have an earned run average of 3.34 this season (1st in the Majors), while The Cardinals have an ERA of 4.15 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Yankees have recorded an impressive 1022 this season, ranking 6th in the MLB. Contrastingly, the Cardinals rank 26th for total strikeouts, recording only 870.

Opponent Batting Average

  • Opponents are batting an average of .226 against the Yankees this season (3rd in the Major Leagues). Comparatively, the Cardinals' opponents are at .253 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 24-20-70 11-10-39 13-10-31 9-7-19 15-13-51 0-0-0 1-2-7
    Yankees 31-28-55 16-12-23 15-16-32 26-20-45 5-8-10 0-0-0 1-4-5

Lead After Three Innings

The Cardinals are +110 to lead after three innings, while the Yankees are -140.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 49-33-32 26-15-19 23-18-13 18-8-9 31-25-23 0-0-0 4-4-2
    Yankees 50-35-29 22-14-15 28-21-14 41-27-23 9-8-6 0-0-0 4-4-2

NRFI/YRFI

The NRFI market is paying -105 and the YRFI is paying -120.

  • The NRFI is 62-52 in Cardinals games this season. The Yankees have a 53-61 NRFI record.

Last Time They Met

The Yankees recorded an upset 2-0 victory over the Cardinals at Yankee Stadium yesterday. George Lombard Jr. went yard en route to that victory, hitting a home run to go with an RBI. That result snapped the Cardinals' three-game winning streak against the Yankees at Yankee Stadium.