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MLB Prop Bets: Boston Red Sox vs San Francisco Giants (August 22, 2026)

The San Francisco Giants (52-76) face the Boston Red Sox (69-59) at Fenway Park on Saturday at 7:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Blade Tidwell is the probable pitcher for the Giants, while Patrick Sandoval is the probable pitcher for the Red Sox. The Red Sox are favored to win at -217, while the Giants are at +177. The total runs line is set at 8.0, with OVER at -113 and UNDER at -106.

  • These teams share a 63-65 Run Line record this season. The Giants are -126 to cover the run line while the Red Sox are +104.
  • The Giants have a 58-58-12 O/U record this season (meaning 58 games have gone over the total runs line, 58 have gone under and 12 have resulted in a push). The Red Sox have a 60-64-4 O/U record.

Scoring Insights

  • The Giants are averaging 4.0 runs per game this season (26th in the league). Comparatively, the Red Sox are averaging +0.5 more at 4.5 runs (13th).
  • In the field, the Giants are allowing 4.6 runs per game this season (20th in the league), while the Red Sox are allowing an average of 3.8 runs (3rd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Giants are at .247 (ranking 10th in the Major leagues), while the Red Sox are batting .251 (6th).

Home Runs

  • In terms of total home runs this season, the Red Sox have hit 132 (T23rd in the Major Leagues). Meanwhile, the Giants have managed 141 (T19th).

Runs Batted In

  • Finally, looking at their runs batted in, the Giants have recorded 497 RBIs to rank T26th in the MLB this season. Comparatively, the Red Sox have recorded 556 RBIs to rank 15th.

Pitching Insights:

Earned Run Average

  • The Red Sox have an earned run average of 3.53 this season (3rd in the Majors), while The Giants have an ERA of 4.36 (23rd).

Strikeouts

  • Turning our attention to total strikeouts, the Giants have recorded 962 this season, ranking 27th in the MLB. Meanwhile, the Red Sox rank 13th for total strikeouts, recording 1095.

Opponent Batting Average

  • Opponents are batting an average of .239 against the Red Sox this season (14th in the Major Leagues). Comparatively, the Giants' opponents are at .247 (19th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Giants 26-32-70 14-9-39 12-23-31 9-6-28 17-26-42 0-0-0 2-3-5
    Red Sox 29-36-63 18-15-31 11-21-32 21-22-44 8-14-19 0-0-0 3-1-6

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Giants 41-53-34 20-23-19 21-30-15 14-15-14 27-38-20 0-0-0 2-4-4
    Red Sox 55-45-28 33-20-11 22-25-17 42-27-18 13-18-10 0-0-0 6-3-1

NRFI/YRFI

The NRFI market is paying -125 and the YRFI is paying -105.

  • The NRFI is 69-59 in Giants games this season. The Red Sox have a 61-67 NRFI record.

Last Time They Met

The Red Sox recorded an upset 6-4 victory over the Giants at Fenway Park yesterday. Willson Contreras went yard en route to that victory, hitting a home run to go with 3 RBIs.