MLB Prop Bets: San Diego Padres vs Minnesota Twins (August 22, 2026)
The Minnesota Twins (63-66) face the San Diego Padres (69-60) at Petco Park on Saturday at 8:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Dean Kremer is the probable pitcher for the Twins, while Casey Mize is the probable pitcher for the Padres. The Padres are favored to win at -164, while the Twins are at +136. The total runs line is set at 8.0, with OVER at -115 and UNDER at -105.
- The Twins (-163) have a 71-58 Run Line record this season, while the Padres (+135) hold a record of 67-62.
- The Twins have a 67-53-9 O/U record this season (meaning 67 games have gone over the total runs line, 53 have gone under and nine have resulted in a push). The Padres have a 56-70-3 O/U record.
Scoring Insights
- The Twins are averaging 4.6 runs per game this season (9th in the league). Comparatively, the Padres are averaging only 4.3 (21st).
- In the field, the Twins are allowing a whopping 5.0 runs per game this season (27th in the league), while the Padres are allowing an average of 4.2 runs (8th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Twins are at .245 (ranking 13th in the Major leagues), while the Padres are batting .238 (22nd).
Home Runs
- In terms of total home runs this season, the Padres have hit 144 (17th in the Major Leagues). Meanwhile, the Twins have managed 147 (15th).
Runs Batted In
- Finally, looking at their runs batted in, the Twins have recorded 566 RBIs to rank 9th in the MLB this season. Comparatively, the Padres have recorded 530 RBIs to rank 21st.
Pitching Insights:
Earned Run Average
- The Padres have an earned run average of 4.03 this season (12th in the Majors), while The Twins have an ERA of 4.63 (26th).
Strikeouts
- Turning our attention to total strikeouts, the Twins have recorded 1067 this season, ranking 17th in the MLB. Meanwhile, the Padres rank T21st for total strikeouts, recording 1043.
Opponent Batting Average
- Opponents are batting an average of .242 against the Padres this season (16th in the Major Leagues). Comparatively, the Twins' opponents are at .252 (25th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Twins | 30-36-63 | 16-11-38 | 14-24-25 | 8-10-20 | 22-26-43 | 0-1-0 | 3-3-4 |
| Padres | 23-24-82 | 13-12-39 | 10-12-41 | 15-9-35 | 8-15-47 | 0-0-2 | 2-1-7 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Twins | 50-52-27 | 28-20-17 | 22-31-10 | 15-13-10 | 35-39-17 | 0-1-0 | 6-4-0 |
| Padres | 43-54-32 | 24-26-14 | 18-27-18 | 19-22-18 | 24-32-14 | 1-1-0 | 4-5-1 |
NRFI/YRFI
The NRFI market is paying -125 and the YRFI is paying -105.
- The NRFI is 54-75 in Twins games this season. The Padres have a 78-51 NRFI record.
Last Time They Met
The Padres recorded a 6-2 victory over the Twins at Petco Park yesterday. Ty France went yard en route to that victory, hitting a home run to go with 3 RBIs.
