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MLB Prop Bets: Houston Astros vs Arizona Diamondbacks (September 4, 2026)

The Arizona Diamondbacks (74-67) face the Houston Astros (71-69) at Daikin Park on Friday at 8:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Merrill Kelly is the probable pitcher for the Diamondbacks, while Cristian Javier is the probable pitcher for the Astros. The Astros are favored to win at -132, while the Diamondbacks are at +109. The total runs line is set at 8.5, with OVER at -117 and UNDER at -103.

  • The Diamondbacks (-194) have a 79-62 Run Line record this season, while the Astros (+159) hold a record of 71-69.
  • The Diamondbacks have a 59-73-9 O/U record this season (meaning 59 games have gone over the total runs line, 73 have gone under and nine have resulted in a push). The Astros have a 71-60-9 O/U record.

Scoring Insights

  • The Diamondbacks are averaging 4.5 runs per game this season (17th in the league). Comparatively, the Astros are averaging 4.5 (12th).
  • In the field, the Diamondbacks are allowing 4.5 runs per game this season (17th in the league), while the Astros are allowing an average of 4.8 runs (24th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Diamondbacks are at .243 (ranking 17th in the Major leagues), while the Astros are batting .240 (20th).

Home Runs

  • In terms of total home runs this season, the Astros are one of the best in the Major Leagues, hitting 184 to rank 5th. Alternatively, the Diamondbacks are at the opposite end of the home run standings, hitting just 138 (26th).

Runs Batted In

  • Finally, looking at their runs batted in, the Diamondbacks have recorded 599 RBIs to rank 15th in the MLB this season. Comparatively, the Astros have recorded 602 RBIs to rank 14th.

Pitching Insights:

Earned Run Average

  • The Astros have an earned run average of 4.58 this season (24th in the Majors), while The Diamondbacks have an ERA of 4.16 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Diamondbacks have recorded 963 this season, ranking 29th in the MLB. Meanwhile, the Astros rank 9th for total strikeouts, recording 1225.

Opponent Batting Average

  • Opponents are batting an average of .239 against the Astros this season (13th in the Major Leagues). Comparatively, the Diamondbacks' opponents are at .249 (20th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Diamondbacks 30-39-72 18-15-37 12-24-33 17-13-28 13-26-44 0-0-2 0-3-7
    Astros 37-36-67 21-14-36 16-22-31 16-14-31 21-22-36 0-0-0 1-2-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Diamondbacks 43-66-32 27-25-18 15-40-14 25-18-15 18-48-17 1-1-0 1-4-5
    Astros 48-57-35 29-26-16 19-31-19 22-26-13 26-31-22 0-0-0 3-2-5

NRFI/YRFI

  • The NRFI is 63-78 in Diamondbacks games this season. The Astros have a 63-77 NRFI record.

Last Time They Met

The Astros recorded a 4-3 victory over the Diamondbacks at Chase Field when these teams last met on July 23, 2025. Ketel Marte was unstoppable in that matchup, hitting a home run, a single and recording an RBI. The Astros have now won six straight at Chase Field against the Diamondbacks.