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MLB Prop Bets: San Francisco Giants vs St. Louis Cardinals (September 9, 2026)

The St. Louis Cardinals (72-74) face the San Francisco Giants (61-85) at Oracle Park on Wednesday at 3:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Andre Pallante is the probable pitcher for the Cardinals, while Blade Tidwell is the probable pitcher for the Giants. The Cardinals are favored to win at -126, while the Giants are at +104. The total runs line is set at 8.0, with OVER at -115 and UNDER at -104.

  • The Cardinals (+130) have an 80-66 Run Line record this season, while the Giants (-157) hold a record of 74-72.
  • The Cardinals have a 66-74-6 O/U record this season (meaning 66 games have gone over the total runs line, 74 have gone under and six have resulted in a push). The Giants have a 67-66-13 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.5 runs per game this season (11th in the league). Comparatively, the Giants are averaging only 4.2 (25th).
  • In the field, the Cardinals are allowing 4.6 runs per game this season (20th in the league), while the Giants are allowing an average of 4.7 runs (T22nd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .243 (ranking 17th in the Major leagues), while the Giants are batting .247 (10th).

Home Runs

  • In terms of total home runs this season, the Giants have hit 166 (T15th in the Major Leagues). Meanwhile, the Cardinals have managed 155 (21st).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 643 RBIs to rank T8th in the MLB this season. Comparatively, the Giants have recorded 589 RBIs to rank 22nd.

Pitching Insights:

Earned Run Average

  • The Giants have an earned run average of 4.35 this season (23rd in the Majors), while The Cardinals have an ERA of 4.29 (21st).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 1151 this season, ranking 24th in the MLB. Meanwhile, the Giants rank 27th for total strikeouts, recording 1094.

Opponent Batting Average

  • Opponents are batting an average of .247 against the Giants this season (19th in the Major Leagues). Comparatively, the Cardinals' opponents are at .254 (26th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 32-29-85 12-12-48 20-17-37 12-12-24 20-17-61 0-0-0 1-6-3
    Giants 36-35-75 20-9-42 16-26-33 11-6-29 25-29-46 0-0-0 5-3-2

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 62-45-39 31-20-21 31-25-18 24-13-11 38-32-28 0-0-0 4-5-1
    Giants 50-58-38 25-24-22 25-34-16 16-15-15 34-43-23 0-0-0 4-4-2

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -110.

  • The NRFI is 76-70 in Cardinals games this season. The Giants have a 72-74 NRFI record.

Last Time They Met

The Giants recorded a 2-1 victory over the Cardinals at Oracle Park yesterday. Christian Koss was unstoppable in that matchup, hitting a home run, a single and recording an RBI. The Giants have now won three straight against the Cardinals.