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MLB Prop Bets: Pittsburgh Pirates vs Milwaukee Brewers (September 17, 2026)

The Milwaukee Brewers (95-57) face the Pittsburgh Pirates (75-77) at PNC Park on Thursday at 12:35pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Kyle Harrison is the probable pitcher for the Brewers, while Wilber Dotel is the probable pitcher for the Pirates. The Brewers are favored to win at -143, while the Pirates are at +119. The total runs line is set at 9.0, with OVER at -105 and UNDER at -115.

  • The Brewers (+113) have a 79-73 Run Line record this season, while the Pirates (-136) hold a record of 70-82.
  • The Brewers have a 68-79-5 O/U record this season (meaning 68 games have gone over the total runs line, 79 have gone under and five have resulted in a push). The Pirates have a 77-68-7 O/U record.

Scoring Insights

  • The Brewers are averaging 5.2 runs per game this season (2nd in the league). Comparatively, the Pirates are averaging 4.8 (5th).
  • In the field, the Brewers are allowing only 3.9 runs per game this season (4th in the league), while the Pirates are allowing an average of 4.6 runs (20th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Brewers are at .259 (ranking 2nd in the Major leagues), while the Pirates are batting .253 (5th).

Home Runs

  • In terms of total home runs this season, the Pirates have hit 174 (16th in the Major Leagues). Meanwhile, the Brewers have managed 146 (T29th).

Runs Batted In

  • Finally, looking at their runs batted in, the Brewers have recorded 744 RBIs to rank 2nd in the MLB this season. Comparatively, the Pirates have recorded 690 RBIs to rank 5th.

Pitching Insights:

Earned Run Average

  • The Pirates have an earned run average of 4.19 this season (17th in the Majors), while The Brewers have an ERA of 3.56 (2nd).

Strikeouts

  • Turning our attention to total strikeouts, the Brewers have recorded 1456 this season, ranking 2nd in the MLB. Meanwhile, the Pirates rank 5th for total strikeouts, recording 1389.

Opponent Batting Average

  • Opponents are batting an average of .237 against the Pirates this season (11th in the Major Leagues). Comparatively, the Brewers' opponents are at .224 (3rd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Brewers 40-31-81 28-14-35 12-17-45 36-24-62 4-7-19 0-0-1 3-1-6
    Pirates 41-27-84 23-13-38 18-14-46 25-10-41 16-17-43 0-0-0 3-1-6

Lead After Three Innings

The Brewers are -135 to lead after three innings, while the Pirates are +105.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Brewers 67-50-35 38-19-20 29-31-14 54-39-29 13-11-6 0-0-1 7-1-2
    Pirates 59-53-40 36-19-19 23-34-21 36-21-19 23-32-21 0-0-0 3-4-3

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -105.

  • The NRFI is 77-75 in Brewers games this season. The Pirates have an 80-72 NRFI record.

Last Time They Met

The Brewers recorded a 5-4 victory over the Pirates at PNC Park yesterday. Brandon Lowe was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs. The Brewers have now won five straight against the Pirates.