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MLB Prop Bets: Chicago Cubs vs Washington Nationals (March 26, 2026)

The Washington Nationals (0-0) face the Chicago Cubs (0-0) at Wrigley Field on Thursday at 2:20pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Cade Cavalli is the probable pitcher for the Nationals, while Matthew Boyd is the probable pitcher for the Cubs. The Cubs are favored to win at -232, while the Nationals are at +189. The total runs line is set at 8.0, with OVER at -108 and UNDER at -112.

  • The Nationals (-110) had a 78-84 Run Line record last season, while the Cubs (-110) held a record of 80-90.
  • The Nationals had an 82-70-10 O/U record last season (meaning 82 games went over the total runs line, 70 went under and 10 resulted in a push). The Cubs had a 77-82-11 O/U record last season.

Scoring Insights

  • The Nationals scored 4.2 runs per game last season (20th in the league). Comparatively, the Cubs averaged 4.9 (5th).
  • In the field, the Nationals allowed a whopping 5.5 runs per game last season (29th in the league), while the Cubs gave up an average of 4.0 runs (T7th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages last season, the Nationals were at .242 (ranking 21st in the Major leagues), while the Cubs batted .249 (13th).

Home Runs

  • In terms of total home runs last season, the Cubs hit 223 (6th in the Major Leagues). Meanwhile, the Nationals managed 161 (24th).

Runs Batted In

  • Finally, looking at their runs batted in, the Nationals recorded 657 RBIs to rank 20th in the MLB last season. Comparatively, the Cubs recorded 771 RBIs to rank T3rd.

Pitching Insights:

Earned Run Average

  • The Cubs had an earned run average of 3.79 last season (9th in the Majors), while The Nationals had an ERA of 5.35 (29th).

Strikeouts

  • Turning our attention to total strikeouts, the Nationals recorded 1248 last season, ranking 28th in the MLB. Meanwhile, the Cubs ranked 27th for total strikeouts, recording 1265.

Opponent Batting Average

  • Opponents batted an average of .239 against the Cubs last season (11th in the Major Leagues). Comparatively, the Nationals' opponents were at .268 (29th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2025.
    Total Home Road Favorite Underdog Neutral
    Nationals 34-46-82 15-24-42 19-22-40 3-5-13 31-41-69 0-0-0
    Cubs 44-38-88 23-16-45 21-22-41 36-24-61 8-14-27 0-0-2

Lead After Three Innings

  • Here are their records after the first three innings in 2025.
    Total Home Road Favorite Underdog Neutral
    Nationals 53-72-37 27-34-20 26-38-17 5-6-10 48-66-27 0-0-0
    Cubs 74-54-42 47-19-18 26-34-24 57-31-33 17-23-9 1-1-0

NRFI/YRFI

The NRFI market is paying -160 and the YRFI is paying +125.

  • The NRFI was 78-84 in Nationals games last season. The Cubs had an 84-86 NRFI record.

Last Time They Met

The Nationals recorded an upset 6-3 victory over the Cubs at Wrigley Field when these teams last met on September 7, 2025. Carson Kelly was crushing the ball in that matchup, hitting 2 home runs and recording 2 RBIs.