

MLB Prop Bets: San Diego Padres vs Chicago Cubs (April 29, 2026)
The Chicago Cubs (18-12) face the San Diego Padres (19-10) at Petco Park on Wednesday at 4:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Jameson Taillon is the probable pitcher for the Cubs, while Matt Waldron is the probable pitcher for the Padres. The total runs line is set at 9.0, with OVER at -105 and UNDER at -115.
- The Cubs (+141) have a 15-15 Run Line record this season, while the Padres (-171) hold a record of 16-13.
- The Cubs have a 19-10-1 O/U record this season (meaning 19 games have gone over the total runs line, 10 have gone under and one has resulted in a push). The Padres have a 13-15-1 O/U record.
Scoring Insights
- The Cubs are averaging 5.5 runs per game this season (3rd in the league). Comparatively, the Padres are averaging only 4.7 (14th).
- In the field, the Cubs are allowing 4.3 runs per game this season (13th in the league), while the Padres are allowing an average of 4.3 runs (14th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cubs are at .261 (ranking 3rd in the Major leagues), while the Padres are batting .238 (17th).
Home Runs
- In terms of total home runs this season, the Padres have hit 27 (T22nd in the Major Leagues). Meanwhile, the Cubs have managed 40 (T4th).
Runs Batted In
- Finally, looking at their runs batted in, the Cubs have recorded 149 RBIs to rank 3rd in the MLB this season. Comparatively, the Padres have recorded 130 RBIs to rank T12th.
Pitching Insights:
Earned Run Average
- The Padres have an earned run average of 4.20 this season (18th in the Majors), while The Cubs have an ERA of 4.01 (14th).
Strikeouts
- Turning our attention to total strikeouts, the Cubs have recorded 243 this season, ranking T20th in the MLB. Meanwhile, the Padres rank 12th for total strikeouts, recording 257.
Opponent Batting Average
- Opponents are batting an average of .244 against the Padres this season (19th in the Major Leagues). Comparatively, the Cubs' opponents are at .232 (10th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cubs | 4-6-20 | 3-2-11 | 1-4-9 | 3-2-14 | 1-4-6 | 0-0-0 | 1-2-7 |
| Padres | 4-4-21 | 3-3-9 | 1-1-10 | 4-2-11 | 0-2-10 | 0-0-2 | 2-1-7 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cubs | 14-8-8 | 8-3-5 | 6-5-3 | 10-3-6 | 4-5-2 | 0-0-0 | 5-2-3 |
| Padres | 7-13-9 | 5-7-3 | 1-5-6 | 4-6-7 | 3-7-2 | 1-1-0 | 1-6-3 |
NRFI/YRFI
The NRFI market is paying -110 and the YRFI is paying -115.
- The NRFI is 20-10 in Cubs games this season. The Padres have a 21-8 NRFI record.
Last Time They Met
The Cubs recorded an 8-3 victory over the Padres at Petco Park yesterday. Despite being on the wrong side of that result, Xander Bogaerts did what he could, hitting a home run.



























