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MLB Prop Bets: Baltimore Orioles vs Houston Astros (April 29, 2026)

The Houston Astros (11-19) face the Baltimore Orioles (14-15) at Oriole Park at Camden Yards on Wednesday at 6:35pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Peter Lambert is the probable pitcher for the Astros, while Chris Bassitt is the probable pitcher for the Orioles. The Orioles are favored to win at -120, while the Astros are at +100. The total runs line is set at 9.0, with OVER at -105 and UNDER at -115.

  • The Astros (+148) have an 11-19 Run Line record this season, while the Orioles (-180) hold a record of 13-16.
  • The Astros have a 21-9-0 O/U record this season (meaning 21 games have gone over the total runs line and nine have gone under). The Orioles have a 17-12-0 O/U record.

Scoring Insights

  • The Astros are averaging 5.1 runs per game this season (6th in the league). Comparatively, the Orioles are averaging 4.5 (15th).
  • In the field, the Astros are allowing a whopping 6.0 runs per game this season (T29th in the league), while the Orioles are allowing an average of 4.9 runs (23rd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Astros are at .260 (ranking 4th in the Major leagues), while the Orioles are batting .240 (14th).

Home Runs

  • In terms of total home runs this season, the Orioles have hit 35 (11th in the Major Leagues). Meanwhile, the Astros have managed 38 (T7th).

Runs Batted In

  • Finally, looking at their runs batted in, the Astros have recorded 146 RBIs to rank 4th in the MLB this season. Comparatively, the Orioles have recorded 129 RBIs to rank T14th.

Pitching Insights:

Earned Run Average

  • The Orioles have an earned run average of 4.28 this season (19th in the Majors), while The Astros have an ERA of 5.96 (30th).

Strikeouts

  • Turning our attention to total strikeouts, the Astros have recorded 274 this season, ranking 4th in the MLB. Meanwhile, the Orioles rank T14th for total strikeouts, recording 252.

Opponent Batting Average

  • Opponents are batting an average of .259 against the Orioles this season (25th in the Major Leagues). Comparatively, the Astros' opponents are at .268 (29th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 11-11-8 7-4-5 4-7-3 4-4-8 7-7-0 0-0-0 4-5-1
    Orioles 4-3-22 3-1-12 1-2-10 3-1-16 1-2-6 0-0-0 3-0-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 11-11-8 7-5-4 4-6-4 6-6-4 5-5-4 0-0-0 3-5-2
    Orioles 9-12-8 7-6-3 2-6-5 6-8-6 3-4-2 0-0-0 4-3-3

NRFI/YRFI

The NRFI market is paying -110 and the YRFI is paying -115.

  • The NRFI is 7-23 in Astros games this season. The Orioles have a 21-8 NRFI record.

Last Time They Met

The Orioles recorded a 5-3 victory over the Astros at Oriole Park at Camden Yards yesterday. Brice Matthews was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs.