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MLB Prop Bets: Milwaukee Brewers vs San Diego Padres (May 12, 2026)

The San Diego Padres (24-16) face the Milwaukee Brewers (22-16) at American Family Field on Tuesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Matt Waldron is the probable pitcher for the Padres, while Brandon Sproat is the probable pitcher for the Brewers. The Brewers are favored to win at -131, while the Padres are at +109. The total runs line is set at 8.5, with OVER at -115 and UNDER at -105.

  • The Padres (-186) have a 19-21 Run Line record this season, while the Brewers (+153) hold a record of 22-16.
  • The Padres have a 16-23-1 O/U record this season (meaning 16 games have gone over the total runs line, 23 have gone under and one has resulted in a push). The Brewers have an 18-19-1 O/U record.

Scoring Insights

  • The Padres are averaging 4.3 runs per game this season (T19th in the league). Comparatively, the Brewers are averaging +0.9 more at 5.1 runs (5th).
  • In the field, the Padres are allowing 4.2 runs per game this season (11th in the league), while the Brewers are allowing an average of 3.7 runs (4th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .223 (ranking 28th in the Major leagues), while the Brewers are batting .240 (15th).

Home Runs

  • In terms of total home runs this season, the Brewers have hit 26 (30th in the Major Leagues). Meanwhile, the Padres have managed 39 (T20th).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 163 RBIs to rank T22nd in the MLB this season. Comparatively, the Brewers have recorded 187 RBIs to rank T7th.

Pitching Insights:

Earned Run Average

  • The Brewers have an earned run average of 3.43 this season (4th in the Majors), while The Padres have an ERA of 4.07 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 350 this season, ranking 15th in the MLB. Meanwhile, the Brewers rank T7th for total strikeouts, recording 366.

Opponent Batting Average

  • Opponents are batting an average of .226 against the Brewers this season (7th in the Major Leagues). Comparatively, the Padres' opponents are at .234 (11th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 5-6-29 4-3-16 1-3-11 5-3-18 0-3-11 0-0-2 1-2-7
    Brewers 9-10-19 4-7-10 5-3-9 8-6-11 1-4-8 0-0-0 5-2-3

Lead After Three Innings

The Padres are +100 to lead after three innings, while the Brewers are -130.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 8-18-14 6-10-7 1-7-7 5-10-11 3-8-3 1-1-0 1-4-5
    Brewers 15-14-9 8-8-5 7-6-4 11-7-7 4-7-2 0-0-0 6-3-1

NRFI/YRFI

The NRFI market is paying -110 and the YRFI is paying -120.

  • The NRFI is 29-11 in Padres games this season. The Brewers have a 19-19 NRFI record.

Last Time They Met

The Brewers recorded a 3-1 victory over the Padres at Petco Park when these teams last met on September 24, 2025. Danny Jansen was unstoppable in that matchup, hitting a home run, a single and recording an RBI. That result snapped the Padres' three-game winning streak against the Brewers.