MLB Prop Bets: Milwaukee Brewers vs St. Louis Cardinals (May 25, 2026)
The St. Louis Cardinals (29-22) face the Milwaukee Brewers (30-20) at American Family Field on Monday at 2:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Matthew Liberatore is the probable pitcher for the Cardinals, while Jacob Misiorowski is the probable pitcher for the Brewers. The Brewers are favored to win at -225, while the Cardinals are at +183. The total runs line is set at 7.5, with OVER at -102 and UNDER at -119.
- The Cardinals (-111) have a 32-19 Run Line record this season, while the Brewers (-108) hold a record of 29-21.
- The Cardinals have a 23-26-2 O/U record this season (meaning 23 games have gone over the total runs line, 26 have gone under and two have resulted in a push). The Brewers have a 23-26-1 O/U record.
Scoring Insights
- The Cardinals are averaging 4.6 runs per game this season (11th in the league). Comparatively, the Brewers are averaging 4.9 (4th).
- In the field, the Cardinals are allowing 4.5 runs per game this season (21st in the league), while the Brewers are allowing an average of 3.6 runs (4th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cardinals are at .242 (ranking 13th in the Major leagues), while the Brewers are batting .246 (9th).
Home Runs
- In terms of total home runs this season, the Brewers have hit 34 (30th in the Major Leagues). Meanwhile, the Cardinals have managed 60 (T10th).
Runs Batted In
- Finally, looking at their runs batted in, the Cardinals have recorded 226 RBIs to rank 11th in the MLB this season. Comparatively, the Brewers have recorded 231 RBIs to rank 8th.
Pitching Insights:
Earned Run Average
- The Brewers have an earned run average of 3.29 this season (4th in the Majors), while The Cardinals have an ERA of 4.20 (21st).
Strikeouts
- Turning our attention to total strikeouts, the Brewers have recorded an impressive 488 this season, ranking 4th in the MLB. Contrastingly, the Cardinals rank 29th for total strikeouts, recording only 380.
Opponent Batting Average
- Opponents are batting an average of only .219 against the Brewers this season (3rd in the Major Leagues). Alternatively, the Cardinals' opponents are at .254 (26th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 8-10-33 | 3-5-18 | 5-5-15 | 1-3-4 | 7-7-29 | 0-0-0 | 1-3-6 |
| Brewers | 14-11-25 | 7-7-13 | 7-4-12 | 11-7-14 | 3-4-11 | 0-0-0 | 5-1-4 |
Lead After Three Innings
The Cardinals are +175 to lead after three innings, while the Brewers are -230.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 21-15-15 | 11-7-8 | 10-8-7 | 4-3-1 | 17-12-14 | 0-0-0 | 4-3-3 |
| Brewers | 24-16-10 | 13-8-6 | 11-8-4 | 15-9-8 | 9-7-2 | 0-0-0 | 8-2-0 |
NRFI/YRFI
The NRFI market is paying -140 and the YRFI is paying +105.
- The NRFI is 28-23 in Cardinals games this season. The Brewers have a 25-25 NRFI record.
Last Time They Met
The Brewers recorded a 6-2 victory over the Cardinals at Busch Stadium when these teams last met on May 6. Andrew Vaughn was unstoppable in that matchup, hitting a home run, a single and recording 3 RBIs.
