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MLB Prop Bets: Chicago Cubs vs St. Louis Cardinals (July 5, 2026)

The St. Louis Cardinals (47-39) face the Chicago Cubs (49-40) at Wrigley Field on Sunday at 2:30pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Matthew Liberatore is the probable pitcher for the Cardinals, while Javier Assad is the probable pitcher for the Cubs. The Cubs are favored to win at -157, while the Cardinals are at +130. The total runs line is set at 8.0, with OVER at -110 and UNDER at -110.

  • The Cardinals (-168) have a 50-36 Run Line record this season, while the Cubs (+139) hold a record of 37-52.
  • The Cardinals have a 37-46-3 O/U record this season (meaning 37 games have gone over the total runs line, 46 have gone under and three have resulted in a push). The Cubs have a 47-40-2 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.6 runs per game this season (11th in the league). Comparatively, the Cubs are averaging 5.0 (5th).
  • In the field, the Cardinals are allowing 4.5 runs per game this season (15th in the league), while the Cubs are allowing an average of 4.6 runs (17th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .248 (ranking 10th in the Major leagues), while the Cubs are batting .244 (15th).

Home Runs

  • In terms of total home runs this season, the Cubs have hit 112 (T10th in the Major Leagues). Meanwhile, the Cardinals have managed 98 (19th).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 387 RBIs to rank 15th in the MLB this season. Comparatively, the Cubs have recorded 420 RBIs to rank T4th.

Pitching Insights:

Earned Run Average

  • The Cubs have an earned run average of 4.36 this season (21st in the Majors), while The Cardinals have an ERA of 4.14 (14th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 647 this season, ranking 28th in the MLB. Meanwhile, the Cubs rank 24th for total strikeouts, recording 700.

Opponent Batting Average

  • Opponents are batting an average of .244 against the Cubs this season (18th in the Major Leagues). Comparatively, the Cardinals' opponents are at .252 (23rd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 16-16-54 5-8-31 11-8-23 6-6-13 10-10-41 0-0-0 1-2-7
    Cubs 16-18-55 10-9-26 6-9-29 14-9-39 2-9-16 0-0-0 1-2-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 37-24-25 18-11-15 19-13-10 13-6-6 24-18-19 0-0-0 4-4-2
    Cubs 34-30-25 22-14-9 12-16-16 29-18-15 5-12-10 0-0-0 2-6-2

NRFI/YRFI

The NRFI market is paying -110 and the YRFI is paying -115.

  • The NRFI is 46-40 in Cardinals games this season. The Cubs have a 53-36 NRFI record.

Last Time They Met

The Cardinals recorded an upset 3-0 victory over the Cubs at Wrigley Field yesterday. JJ Wetherholt was unstoppable in that matchup, hitting a home run, a double and recording an RBI. The Cardinals have now won three straight against the Cubs.