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MLB Prop Bets: Cleveland Guardians vs San Diego Padres (August 15, 2026)

The San Diego Padres (66-57) face the Cleveland Guardians (59-64) at Progressive Field on Saturday at 7:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Randy Vasquez is the probable pitcher for the Padres, while Joey Cantillo is the probable pitcher for the Guardians.

  • The Padres have a 56-65-2 O/U record this season (meaning 56 games have gone over the total runs line, 65 have gone under and two have resulted in a push). The Guardians have a 60-63-0 O/U record.

Scoring Insights

  • The Padres are averaging 4.3 runs per game this season (21st in the league). Comparatively, the Guardians are averaging 4.0 (28th).
  • In the field, the Padres are allowing 4.3 runs per game this season (T11th in the league), while the Guardians are allowing an average of 4.2 runs (9th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .239 (ranking 22nd in the Major leagues), while the Guardians are batting .233 (27th).

Home Runs

  • In terms of total home runs this season, the Guardians have hit 119 (T27th in the Major Leagues). Meanwhile, the Padres have managed 136 (19th).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 511 RBIs to rank 20th in the MLB this season. Comparatively, the Guardians have recorded 467 RBIs to rank 28th.

Pitching Insights:

Earned Run Average

  • The Guardians have an earned run average of 3.86 this season (9th in the Majors), while The Padres have an ERA of 4.09 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 1000 this season, ranking T19th in the MLB. Meanwhile, the Guardians rank 4th for total strikeouts, recording 1139.

Opponent Batting Average

  • Opponents are batting an average of .239 against the Guardians this season (12th in the Major Leagues). Comparatively, the Padres' opponents are at .245 (18th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 21-23-79 12-12-39 9-11-38 13-9-33 8-14-46 0-0-2 3-0-7
    Guardians 27-19-77 16-9-35 11-10-42 18-11-44 9-8-33 0-0-0 3-0-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 40-52-31 23-26-14 16-25-17 16-22-17 24-30-14 1-1-0 4-6-0
    Guardians 43-39-41 26-18-16 17-21-25 28-24-21 15-15-20 0-0-0 2-6-2

NRFI/YRFI

  • The NRFI is 76-47 in Padres games this season. The Guardians have a 72-51 NRFI record.

Last Time They Met

The Padres recorded a 7-5 victory over the Guardians at Progressive Field yesterday. Nathaniel Lowe was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs. The Padres have now won six straight against the Guardians.