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MLB Prop Bets: Cincinnati Reds vs St. Louis Cardinals Game 1 (August 17, 2026)

The St. Louis Cardinals (62-61) face the Cincinnati Reds (59-63) at Great American Ball Park on Monday at 1:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Andre Pallante is the probable pitcher for the Cardinals, while Rhett Lowder is the probable pitcher for the Reds.

  • The Cardinals have a 49-69-5 O/U record this season (meaning 49 games have gone over the total runs line, 69 have gone under and five have resulted in a push). The Reds have a 64-57-1 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.4 runs per game this season (19th in the league). Comparatively, the Reds are averaging 4.1 (24th).
  • In the field, the Cardinals are allowing 4.4 runs per game this season (14th in the league), while the Reds are allowing an average of 4.8 runs (22nd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .239 (ranking 21st in the Major leagues), while the Reds are batting .227 (30th).

Home Runs

  • In terms of total home runs this season, the Reds have hit 160 (6th in the Major Leagues). Meanwhile, the Cardinals have managed 127 (22nd).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 524 RBIs to rank 16th in the MLB this season. Comparatively, the Reds have recorded 478 RBIs to rank 27th.

Pitching Insights:

Earned Run Average

  • The Reds have an earned run average of 4.50 this season (24th in the Majors), while The Cardinals have an ERA of 4.04 (12th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 935 this season, ranking 26th in the MLB. Meanwhile, the Reds rank 22nd for total strikeouts, recording 984.

Opponent Batting Average

  • Opponents are batting an average of .247 against the Reds this season (20th in the Major Leagues). Comparatively, the Cardinals' opponents are at .252 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 26-20-77 12-10-44 14-10-33 10-7-21 16-13-56 0-0-0 2-0-8
    Reds 26-32-64 12-14-36 14-18-28 11-9-20 15-23-44 0-0-0 2-3-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 52-35-36 29-17-20 23-18-16 20-9-9 32-26-27 0-0-0 3-3-4
    Reds 37-48-37 20-21-21 17-27-16 15-13-12 22-35-25 0-0-0 2-4-4

NRFI/YRFI

  • The NRFI is 68-55 in Cardinals games this season. The Reds have a 61-61 NRFI record.

Last Time They Met

The Reds recorded a 5-3 extra innings victory over the Cardinals at Busch Stadium when these teams last met on July 26. Elly De La Cruz was unstoppable in that matchup, hitting a home run, a single and recording an RBI.