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MLB Prop Bets: Baltimore Orioles vs Cleveland Guardians (September 7, 2026)

The Cleveland Guardians (73-71) face the Baltimore Orioles (69-75) at Oriole Park at Camden Yards on Monday at 1:35pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Joey Cantillo is the probable pitcher for the Guardians, while Trevor Rogers is the probable pitcher for the Orioles. The Orioles are favored to win at -131, while the Guardians are at +109. The total runs line is set at 8.5, with OVER at -102 and UNDER at -118.

  • The Guardians (-199) have a 64-80 Run Line record this season, while the Orioles (+163) hold a record of 73-71.
  • The Guardians have a 67-76-1 O/U record this season (meaning 67 games have gone over the total runs line, 76 have gone under and one has resulted in a push). The Orioles have a 69-70-5 O/U record.

Scoring Insights

  • The Guardians are averaging 4.0 runs per game this season (T28th in the league). Comparatively, the Orioles are averaging +0.4 more at 4.5 runs (16th).
  • In the field, the Guardians are allowing 4.1 runs per game this season (7th in the league), while the Orioles are allowing an average of 4.7 runs (22nd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Guardians are at .236 (ranking 24th in the Major leagues), while the Orioles are batting .234 (26th).

Home Runs

  • In terms of total home runs this season, the Orioles have hit 172 (11th in the Major Leagues). Meanwhile, the Guardians have managed 134 (29th).

Runs Batted In

  • Finally, looking at their runs batted in, the Guardians have recorded 557 RBIs to rank 27th in the MLB this season. Comparatively, the Orioles have recorded 618 RBIs to rank 12th.

Pitching Insights:

Earned Run Average

  • The Orioles have an earned run average of 4.13 this season (16th in the Majors), while The Guardians have an ERA of 3.75 (7th).

Strikeouts

  • Turning our attention to total strikeouts, the Guardians have recorded 1355 this season, ranking 3rd in the MLB. Meanwhile, the Orioles rank T20th for total strikeouts, recording 1162.

Opponent Batting Average

  • Opponents are batting an average of .253 against the Orioles this season (25th in the Major Leagues). Comparatively, the Guardians' opponents are at .237 (10th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Guardians 31-26-87 19-13-43 12-13-44 22-17-53 9-9-34 0-0-0 1-4-5
    Orioles 27-28-89 11-11-50 16-17-39 11-9-48 16-19-41 0-0-0 1-2-7

Lead After Three Innings

The Guardians are +105 to lead after three innings, while the Orioles are -135.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Guardians 51-47-46 32-24-19 19-23-27 36-30-26 15-17-20 0-0-0 3-5-2
    Orioles 47-58-39 24-28-20 23-30-19 23-24-21 24-34-18 0-0-0 3-4-3

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -110.

  • The NRFI is 81-63 in Guardians games this season. The Orioles also have an 81-63 NRFI record.

Last Time They Met

The Guardians recorded an 8-4 victory over the Orioles at Progressive Field when these teams last met on April 19. Jose Ramirez was crushing the ball in that matchup, hitting 2 home runs and recording 2 RBIs.