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MLB Prop Bets: Tampa Bay Rays vs Houston Astros (September 12, 2026)

The Houston Astros (75-73) face the Tampa Bay Rays (88-59) at Tropicana Field on Saturday at 6:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Peter Lambert is the probable pitcher for the Astros, while Ian Seymour is the probable pitcher for the Rays. The Rays are favored to win at -149, while the Astros are at +123. The total runs line is set at 8.0, with OVER at -106 and UNDER at -114.

  • The Astros (-175) have a 76-72 Run Line record this season, while the Rays (+144) hold a record of 81-66.
  • The Astros have a 73-66-9 O/U record this season (meaning 73 games have gone over the total runs line, 66 have gone under and nine have resulted in a push). The Rays have a 68-75-4 O/U record.

Scoring Insights

  • The Astros are averaging 4.5 runs per game this season (15th in the league). Comparatively, the Rays are averaging 4.5 (12th).
  • In the field, the Astros are allowing 4.8 runs per game this season (24th in the league), while the Rays are allowing an average of 4.1 runs (8th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Astros are at .241 (ranking 20th in the Major leagues), while the Rays are batting .260 (1st).

Home Runs

  • In terms of total home runs this season, the Rays have hit 157 (21st in the Major Leagues). Meanwhile, the Astros have managed 193 (5th).

Runs Batted In

  • Finally, looking at their runs batted in, the Astros have recorded 632 RBIs to rank 15th in the MLB this season. Comparatively, the Rays have recorded 633 RBIs to rank 14th.

Pitching Insights:

Earned Run Average

  • The Rays have an earned run average of 3.79 this season (7th in the Majors), while The Astros have an ERA of 4.51 (24th).

Strikeouts

  • Turning our attention to total strikeouts, the Astros have recorded 1296 this season, ranking 9th in the MLB. Meanwhile, the Rays rank 21st for total strikeouts, recording 1183.

Opponent Batting Average

  • Opponents are batting an average of .231 against the Rays this season (4th in the Major Leagues). Comparatively, the Astros' opponents are at .238 (12th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 39-36-73 23-14-38 16-22-35 18-14-32 21-22-41 0-0-0 2-0-8
    Rays 34-28-85 17-13-43 17-15-42 25-21-52 9-7-33 0-0-0 1-1-8

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 53-58-37 32-27-16 21-31-21 24-27-13 29-31-24 0-0-0 5-1-4
    Rays 60-42-45 28-22-23 32-20-22 44-30-24 16-12-21 0-0-0 5-1-4

NRFI/YRFI

  • The NRFI is 69-79 in Astros games this season. The Rays have a 79-68 NRFI record.

Last Time They Met

The Rays recorded an upset 3-1 victory over the Astros at Tropicana Field yesterday. Victor Mesa Jr. went yard en route to that victory, hitting a home run to go with an RBI. That result snapped the Astros' five-game winning streak against the Rays at Tropicana Field.