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MLB Prop Bets: Detroit Tigers vs Washington Nationals (September 21, 2026)

The Washington Nationals (73-83) face the Detroit Tigers (73-83) at Comerica Park on Monday at 6:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. DJ Herz is the probable pitcher for the Nationals, while River Ryan is the probable pitcher for the Tigers. The Tigers are favored to win at -156, while the Nationals are at +129. The total runs line is set at 8.0, with OVER at -117 and UNDER at -102.

  • The Nationals (-167) have an 88-68 Run Line record this season, while the Tigers (+138) hold a record of 78-78.
  • The Nationals have an 82-67-7 O/U record this season (meaning 82 games have gone over the total runs line, 67 have gone under and seven have resulted in a push). The Tigers have a 67-82-7 O/U record.

Scoring Insights

  • The Nationals are averaging 5.1 runs per game this season (3rd in the league). Comparatively, the Tigers are averaging only 4.5 (T13th).
  • In the field, the Nationals are allowing a whopping 5.0 runs per game this season (27th in the league), while the Tigers are allowing an average of 4.0 runs (7th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Nationals are at .247 (ranking 10th in the Major leagues), while the Tigers are batting .240 (21st).

Home Runs

  • In terms of total home runs this season, the Tigers have hit 173 (19th in the Major Leagues). Meanwhile, the Nationals have managed 203 (5th).

Runs Batted In

  • Finally, looking at their runs batted in, the Nationals have recorded 756 RBIs to rank 3rd in the MLB this season. Comparatively, the Tigers have recorded 662 RBIs to rank T16th.

Pitching Insights:

Earned Run Average

  • The Tigers have one of the strongest earned run averages this season, sitting at 3.66 (6th in the Majors), while the Nationals are at the opposite end of the scale with an ERA of 4.66 (26th).

Strikeouts

  • Turning our attention to total strikeouts, the Nationals have recorded 1227 this season, ranking 25th in the MLB. Meanwhile, the Tigers rank 23rd for total strikeouts, recording 1253.

Opponent Batting Average

  • Opponents are batting an average of only .232 against the Tigers this season (5th in the Major Leagues). Alternatively, the Nationals' opponents are at .253 (25th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Nationals 42-34-80 24-12-42 18-22-38 15-5-19 27-29-61 0-0-0 4-3-3
    Tigers 42-29-85 15-11-49 27-18-36 27-16-43 15-13-42 0-0-0 2-4-4

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Nationals 62-52-42 36-19-23 26-33-19 21-6-12 41-46-30 0-0-0 4-4-2
    Tigers 70-52-34 36-24-15 34-28-19 40-30-16 30-22-18 0-0-0 2-6-2

NRFI/YRFI

The NRFI market is paying -125 and the YRFI is paying -105.

  • The NRFI is 77-79 in Nationals games this season. The Tigers have a 78-78 NRFI record.

Last Time They Met

The Nationals recorded an 11-7 victory over the Tigers at Nationals Park when these teams last met on July 3, 2025. James Wood dominated at the plate in that matchup, notching 1 home run, 4 singles and 2 RBIs.