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MLB Prop Bets: Chicago Cubs vs Miami Marlins (September 23, 2026)

The Miami Marlins (77-80) face the Chicago Cubs (87-70) at Wrigley Field on Wednesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Ryan Gusto is the probable pitcher for the Marlins, while Kevin Gausman is the probable pitcher for the Cubs. The Cubs are favored to win at -179, while the Marlins are at +148. The total runs line is set at 7.0, with OVER at +104 and UNDER at -125.

  • The Marlins (-156) have a 79-78 Run Line record this season, while the Cubs (+129) hold a record of 78-79.
  • The Marlins have an 81-73-3 O/U record this season (meaning 81 games have gone over the total runs line, 73 have gone under and three have resulted in a push). The Cubs have an 87-65-5 O/U record.

Scoring Insights

  • The Marlins are averaging 4.5 runs per game this season (T15th in the league). Comparatively, the Cubs are averaging +0.9 more at 5.3 runs (1st).
  • In the field, the Marlins are allowing 4.4 runs per game this season (16th in the league), while the Cubs are allowing an average of 4.4 runs (12th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Marlins are at .249 (ranking 7th in the Major leagues), while the Cubs are batting .251 (6th).

Home Runs

  • In terms of total home runs this season, the Cubs have hit 217 (T1st in the Major Leagues). Meanwhile, the Marlins have managed 162 (T23rd).

Runs Batted In

  • Finally, looking at their runs batted in, the Marlins have recorded 670 RBIs to rank T15th in the MLB this season. Comparatively, the Cubs have recorded 791 RBIs to rank 1st.

Pitching Insights:

Earned Run Average

  • The Cubs have an earned run average of 4.17 this season (18th in the Majors), while The Marlins have an ERA of 4.13 (14th).

Strikeouts

  • Turning our attention to total strikeouts, the Marlins have recorded 1282 this season, ranking 19th in the MLB. Meanwhile, the Cubs rank 26th for total strikeouts, recording 1226.

Opponent Batting Average

  • Opponents are batting an average of .243 against the Cubs this season (17th in the Major Leagues). Comparatively, the Marlins' opponents are at .236 (9th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Marlins 28-29-100 15-13-50 13-16-50 14-9-46 14-20-54 0-0-0 0-2-8
    Cubs 37-32-88 25-16-38 12-16-50 32-19-59 5-13-29 0-0-0 3-3-4

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Marlins 59-58-40 35-23-20 24-35-20 29-18-22 30-40-18 0-0-0 4-3-3
    Cubs 64-48-45 41-20-18 23-28-27 54-28-28 10-20-17 0-0-0 7-2-1

NRFI/YRFI

  • The NRFI is 93-64 in Marlins games this season. The Cubs have an 83-74 NRFI record.

Last Time They Met

The Marlins recorded an 8-2 extra innings victory over the Cubs at Wrigley Field yesterday. Kyle Stowers was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs.