MLB Prop Bets: Chicago White Sox vs Tampa Bay Rays (September 10, 2025)

The Tampa Bay Rays (72-72) face the Chicago White Sox (55-90) at Rate Field on Wednesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Ryan Pepiot is the probable pitcher for the Rays, while the White Sox's probable pitcher remains unclear.

  • The Rays have a 62-73-9 O/U record this season (meaning 62 games have gone over the total runs line, 73 have gone under and nine have resulted in a push). The White Sox have a 68-67-10 O/U record.

Scoring Insights

  • The Rays are averaging 4.5 runs per game this season (14th in the league). Comparatively, the White Sox are averaging only 4.0 (26th).
  • In the field, the Rays are allowing 4.1 runs per game this season (9th in the league), while the White Sox are allowing an average of 4.6 runs (21st).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Rays are at .252 (ranking 8th in the Major leagues), while the White Sox are batting .235 (27th).

Home Runs

  • In terms of total home runs this season, the White Sox have hit 149 (21st in the Major Leagues). Meanwhile, the Rays have managed 163 (15th).

Runs Batted In

  • Finally, looking at their runs batted in, the Rays have recorded 617 RBIs to rank 13th in the MLB this season. Comparatively, the White Sox have recorded 566 RBIs to rank 26th.

Pitching Insights:

Earned Run Average

  • The White Sox have an earned run average of 4.24 this season (20th in the Majors), while The Rays have an ERA of 3.85 (9th).

Strikeouts

  • Turning our attention to total strikeouts, the Rays have recorded 1260 this season, ranking 7th in the MLB. Meanwhile, the White Sox rank 26th for total strikeouts, recording 1129.

Opponent Batting Average

  • Opponents are batting an average of .247 against the White Sox this season (21st in the Major Leagues). Comparatively, the Rays' opponents are at .235 (6th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Rays 37-35-72 23-18-33 14-17-39 22-16-36 15-19-36 0-0-0 4-1-5
    White Sox 30-44-71 17-18-38 13-26-33 1-1-1 29-43-70 0-0-0 2-5-3

Lead After Three Innings

  • Here are their records after the first three innings in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Rays 54-53-37 29-32-13 25-21-24 33-24-17 21-29-20 0-0-0 7-1-2
    White Sox 45-57-43 25-25-23 20-32-20 1-0-2 44-57-41 0-0-0 2-5-3

NRFI/YRFI

  • The NRFI is 69-75 in Rays games this season. The White Sox have a 65-80 NRFI record.

Last Time They Met

The Rays recorded a 5-4 victory over the White Sox at Rate Field yesterday. Tristan Gray went yard en route to that victory, hitting a home run to go with an RBI. That result snapped the White Sox's four-game winning streak against the Rays at Rate Field.