

MLB Prop Bets: Baltimore Orioles vs Pittsburgh Pirates (September 10, 2025)
The Pittsburgh Pirates (64-81) face the Baltimore Orioles (67-77) at Oriole Park at Camden Yards on Wednesday at 6:35pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Paul Skenes is the probable pitcher for the Pirates, while Tyler Wells is the probable pitcher for the Orioles. The Pirates are favored to win at -148, while the Orioles are at +122. The total runs line is set at 7.5, with OVER at -103 and UNDER at -120.
- The Pirates (+119) have a 79-66 Run Line record this season, while the Orioles (-145) hold a record of 69-75.
- The Pirates have a 58-81-6 O/U record this season (meaning 58 games have gone over the total runs line, 81 have gone under and six have resulted in a push). The Orioles have a 61-77-6 O/U record.
Scoring Insights
- The Pirates are averaging 3.6 runs per game this season (30th in the league). Comparatively, the Orioles are averaging +0.7 more at 4.3 runs (T18th).
- In the field, the Pirates are allowing 4.1 runs per game this season (T7th in the league), while the Orioles are allowing an average of 4.9 runs (25th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Pirates are at .232 (ranking 28th in the Major leagues), while the Orioles are batting .240 (22nd).
Home Runs
- In terms of total home runs this season, the Orioles have hit 173 (T12th in the Major Leagues). Meanwhile, the Pirates have managed 103 (30th).
Runs Batted In
- Finally, looking at their runs batted in, the Pirates have recorded 504 RBIs to rank 30th in the MLB this season. Comparatively, the Orioles have recorded 590 RBIs to rank 22nd.
Pitching Insights:
Earned Run Average
- The Orioles have an earned run average of 4.63 this season (25th in the Majors), while The Pirates have an ERA of 3.89 (13th).
Strikeouts
- Turning our attention to total strikeouts, the Pirates have recorded 1153 this season, ranking 22nd in the MLB. Meanwhile, the Orioles rank 20th for total strikeouts, recording 1181.
Opponent Batting Average
- Opponents are batting an average of .261 against the Orioles this season (28th in the Major Leagues). Comparatively, the Pirates' opponents are at .237 (8th).
First Innings Moneyline
- Here are their first innings moneyline records in 2025.
Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
---|---|---|---|---|---|---|---|
Pirates | 31-26-88 | 17-13-45 | 14-13-43 | 10-3-28 | 21-23-60 | 0-0-0 | 3-2-5 |
Orioles | 26-39-79 | 15-18-39 | 11-21-40 | 16-18-31 | 10-21-48 | 0-0-0 | 2-4-4 |
Lead After Three Innings
The Pirates are -159 to lead after three innings, while the Orioles are +124.
- Here are their records after the first three innings in 2025.
Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
---|---|---|---|---|---|---|---|
Pirates | 54-46-45 | 34-22-19 | 20-24-26 | 19-12-10 | 35-34-35 | 0-0-0 | 4-1-5 |
Orioles | 54-59-31 | 31-24-17 | 23-35-14 | 30-21-14 | 24-38-17 | 0-0-0 | 3-4-3 |
NRFI/YRFI
The NRFI market is paying -155 and the YRFI is paying +115.
- The NRFI is 82-63 in Pirates games this season. The Orioles have a 74-70 NRFI record.
Last Time They Met
The Orioles recorded a 3-2 extra innings victory over the Pirates at Oriole Park at Camden Yards yesterday. Jeremiah Jackson was unstoppable in that matchup, hitting a home run, a single and recording an RBI.