MLB Prop Bets: Toronto Blue Jays vs Houston Astros (September 10, 2025)

The Houston Astros (78-67) face the Toronto Blue Jays (83-61) at Rogers Centre on Wednesday at 7:07pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Jason Alexander is the probable pitcher for the Astros, while Jose Berrios is the probable pitcher for the Blue Jays. The Blue Jays are favored to win at -137, while the Astros are at +112. The total runs line is set at 9.0, with OVER at -106 and UNDER at -115.

  • The Astros (-186) have a 71-74 Run Line record this season, while the Blue Jays (+152) hold a record of 83-61.
  • The Astros have a 65-72-8 O/U record this season (meaning 65 games have gone over the total runs line, 72 have gone under and eight have resulted in a push). The Blue Jays have a 79-60-5 O/U record.

Scoring Insights

  • The Astros are averaging 4.2 runs per game this season (25th in the league). Comparatively, the Blue Jays are averaging +0.8 more at 5.0 runs (4th).
  • In the field, the Astros are allowing 4.1 runs per game this season (T7th in the league), while the Blue Jays are allowing an average of 4.5 runs (19th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Astros are at .253 (ranking 6th in the Major leagues), while the Blue Jays are batting .269 (1st).

Home Runs

  • In terms of total home runs this season, the Blue Jays have hit 175 (11th in the Major Leagues). Meanwhile, the Astros have managed 160 (18th).

Runs Batted In

  • Finally, looking at their runs batted in, the Astros have recorded 584 RBIs to rank 23rd in the MLB this season. Comparatively, the Blue Jays have recorded 694 RBIs to rank 4th.

Pitching Insights:

Earned Run Average

  • The Blue Jays have an earned run average of 4.23 this season (19th in the Majors), while The Astros have an ERA of 3.85 (8th).

Strikeouts

  • Turning our attention to total strikeouts, the Astros have recorded 1375 this season, ranking 1st in the MLB. Meanwhile, the Blue Jays rank 6th for total strikeouts, recording 1275.

Opponent Batting Average

  • Opponents are batting an average of .241 against the Blue Jays this season (11th in the Major Leagues). Comparatively, the Astros' opponents are at .231 (5th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 28-32-85 13-18-44 15-14-41 15-21-59 13-11-26 0-0-0 1-0-9
    Blue Jays 32-36-76 17-16-37 15-20-39 17-15-38 15-21-38 0-0-0 3-2-5

Lead After Three Innings

The Astros are -115 to lead after three innings, while the Blue Jays are -115.

  • Here are their records after the first three innings in 2025.
    Total Home Road Favorite Underdog Neutral Last 10
    Astros 51-55-39 27-33-15 24-22-24 33-37-25 18-18-14 0-0-0 3-4-3
    Blue Jays 52-58-34 29-26-15 23-32-19 33-26-11 19-32-23 0-0-0 2-5-3

NRFI/YRFI

The NRFI market is paying +110 and the YRFI is paying -145.

  • The NRFI is 82-63 in Astros games this season. The Blue Jays have a 71-73 NRFI record.

Last Time They Met

The Blue Jays recorded a 4-3 extra innings victory over the Astros at Rogers Centre yesterday. Despite being on the wrong side of that result, Carlos Correa went yard in that matchup, hitting a home run to go with 2 RBIs. That result snapped the Astros' five-game winning streak against the Blue Jays.