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MLB Prop Bets: Detroit Tigers vs St. Louis Cardinals (April 5, 2026)

The St. Louis Cardinals (4-4) face the Detroit Tigers (4-4) at Comerica Park on Sunday at 7:20pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Kyle Leahy is the probable pitcher for the Cardinals, while Keider Montero is the probable pitcher for the Tigers. The Tigers are favored to win at -143, while the Cardinals are at +119. The total runs line is set at 8.0, with OVER at -104 and UNDER at -115.

  • The Cardinals (-181) have an 83-87 Run Line record since the beginning of last season, while the Tigers (+149) hold a record of 82-96 across the same span.
  • The Cardinals have an 85-77-8 O/U record since the beginning of last season (meaning 85 games have gone over the total runs line, 77 have gone under and eight have resulted in a push). The Tigers have a 90-78-10 O/U record.

Scoring Insights

  • The Cardinals have scored 4.3 runs per game since the beginning of last season (21st in the league). Comparatively, the Tigers have averaged 4.7 over the same span (10th).
  • In the field, the Cardinals have allowed 4.7 runs per game since the beginning of last season (21st in the league), while the Tigers have allowed an average of 4.2 runs over that span (15th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages since the beginning of last season, the Cardinals are at .244 (ranking 19th in the Major leagues), while the Tigers are batting .247 (16th).

Home Runs

  • In terms of total home runs since the beginning of last season, the Tigers have hit 204 (10th in the Major Leagues). Meanwhile, the Cardinals have managed 156 (28th).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 687 RBIs to rank 21st in the MLB since the beginning of last season. Comparatively, the Tigers have recorded 762 RBIs to rank 11th.

Pitching Insights:

Earned Run Average

  • The Tigers have an earned run average of 3.93 since the beginning of last season (15th in the Majors), while The Cardinals have an ERA of 4.33 (21st).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 1256 since the beginning of last season, ranking 29th in the MLB. Meanwhile, the Tigers rank 15th for total strikeouts, recording 1436.

Opponent Batting Average

  • Opponents are batting an average of .240 against the Tigers since the beginning of last season (13th in the Major Leagues). Comparatively, the Cardinals' opponents are at .261 (28th).

First Innings Moneyline

  • Here are their first innings moneyline records since the beginning of last season.
    Total Home Road Favorite Underdog Neutral
    Cardinals 31-52-87 13-28-46 18-24-41 10-22-32 21-30-55 0-0-0
    Tigers 42-37-99 24-15-46 18-22-53 28-22-66 14-15-33 0-0-0

Lead After Three Innings

  • Here are their records after the first three innings since the beginning of last season.
    Total Home Road Favorite Underdog Neutral
    Cardinals 58-63-49 32-28-27 26-35-22 26-25-13 32-38-36 0-0-0
    Tigers 77-63-38 40-26-19 37-37-19 53-35-28 24-28-10 0-0-0

NRFI/YRFI

  • The NRFI is 85-85 in Cardinals games since the beginning of last season. The Tigers have a 98-80 NRFI record.

Last Time They Met

The Tigers recorded an upset 11-6 victory over the Cardinals at Comerica Park yesterday. Jordan Walker dominated at the plate in that matchup, notching 1 home run, 2 singles and 5 RBIs. The Tigers have now won four straight against the Cardinals.