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MLB Prop Bets: Chicago White Sox vs Baltimore Orioles (April 6, 2026)

The Baltimore Orioles (3-6) face the Chicago White Sox (4-5) at Rate Field on Monday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Grant Taylor is the probable pitcher for the White Sox, while the Orioles' probable pitcher remains unclear. The Orioles are favored to win at -149, while the White Sox are at +123. The total runs line is set at 9.0, with OVER at -101 and UNDER at -119.

  • The Orioles (+104) have an 80-91 Run Line record since the beginning of last season, while the White Sox (-126) hold a record of 98-73 across the same span.
  • The Orioles have a 70-94-7 O/U record since the beginning of last season (meaning 70 games have gone over the total runs line, 94 have gone under and seven have resulted in a push). The White Sox have an 81-79-11 O/U record.

Scoring Insights

  • The Orioles have scored 4.2 runs per game since the beginning of last season (24th in the league). Comparatively, the White Sox have averaged 4.0 over the same span (27th).
  • In the field, the Orioles have allowed 4.9 runs per game since the beginning of last season (24th in the league), while the White Sox have allowed an average of 4.7 runs over that span (22nd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages since the beginning of last season, the Orioles are at .236 (ranking 24th in the Major leagues), while the White Sox are batting .232 (28th).

Home Runs

  • In terms of total home runs since the beginning of last season, the White Sox have hit 175 (23rd in the Major Leagues). Meanwhile, the Orioles have managed 197 (14th).

Runs Batted In

  • Finally, looking at their runs batted in, the Orioles have recorded 677 RBIs to rank 25th in the MLB since the beginning of last season. Comparatively, the White Sox have recorded 657 RBIs to rank 27th.

Pitching Insights:

Earned Run Average

  • The White Sox have an earned run average of 4.36 since the beginning of last season (22nd in the Majors), while The Orioles have an ERA of 4.61 (26th).

Strikeouts

  • Turning our attention to total strikeouts, the Orioles have recorded 1429 since the beginning of last season, ranking 19th in the MLB. Meanwhile, the White Sox rank T25th for total strikeouts, recording 1355.

Opponent Batting Average

  • Opponents are batting an average of .249 against the White Sox since the beginning of last season (22nd in the Major Leagues). Comparatively, the Orioles' opponents are at .259 (27th).

First Innings Moneyline

  • Here are their first innings moneyline records since the beginning of last season.
    Total Home Road Favorite Underdog Neutral
    Orioles 29-48-94 16-21-50 13-27-44 17-20-39 12-28-55 0-0-0
    White Sox 43-49-79 25-20-39 18-29-40 2-1-1 41-48-78 0-0-0

Lead After Three Innings

  • Here are their records after the first three innings since the beginning of last season.
    Total Home Road Favorite Underdog Neutral
    Orioles 61-71-39 35-31-21 26-40-18 33-25-18 28-46-21 0-0-0
    White Sox 57-65-49 32-27-25 25-38-24 1-0-3 56-65-46 0-0-0

NRFI/YRFI

The NRFI market is paying -130 and the YRFI is paying +100.

  • The NRFI is 87-84 in Orioles games since the beginning of last season. The White Sox have a 73-98 NRFI record.

Last Time They Met

The Orioles recorded a 3-1 victory over the White Sox at Rate Field when these teams last met on September 17, 2025. Dylan Beavers went yard en route to that victory, hitting a home run to go with 2 RBIs. The Orioles have now won eight straight at Rate Field against the White Sox.