MLB Prop Bets: Chicago Cubs vs Cincinnati Reds (May 6, 2026)
The Cincinnati Reds (20-16) face the Chicago Cubs (24-12) at Wrigley Field on Wednesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Brady Singer is the probable pitcher for the Reds, while Colin Rea is the probable pitcher for the Cubs. The Cubs are favored to win at -175, while the Reds are at +144. The total runs line is set at 8.0, with OVER at -106 and UNDER at -114.
- The Reds (-149) have a 22-14 Run Line record this season, while the Cubs (+123) hold a record of 18-18.
- The Reds have a 21-15-0 O/U record this season (meaning 21 games have gone over the total runs line and 15 have gone under). The Cubs have a 21-13-2 O/U record.
Scoring Insights
- The Reds are averaging 4.1 runs per game this season (T22nd in the league). Comparatively, the Cubs are averaging +1.3 more at 5.4 runs (3rd).
- In the field, the Reds are allowing 4.8 runs per game this season (20th in the league), while the Cubs are allowing an average of 4.1 runs (8th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cubs are at an impressive .258 (ranking 4th in the Major leagues), while the Reds are batting an underwhelming .218 (30th).
Home Runs
- In terms of total home runs this season, the Cubs have hit 47 (T4th in the Major Leagues). Meanwhile, the Reds have managed 48 (3rd).
Runs Batted In
- Finally, looking at their runs batted in, the Cubs have been outstanding this season, recording 177 RBIs to rank 3rd in the MLB. Comparatively, the Reds have performed poorly in this area, recording only 136 RBIs to rank 27th.
Pitching Insights:
Earned Run Average
- The Cubs have an earned run average of 3.83 this season (8th in the Majors), while The Reds have an ERA of 4.45 (21st).
Strikeouts
- Turning our attention to total strikeouts, the Reds have recorded 280 this season, ranking T23rd in the MLB. Meanwhile, the Cubs rank T18th for total strikeouts, recording 299.
Opponent Batting Average
- Opponents are batting an average of .227 against the Cubs this season (7th in the Major Leagues). Comparatively, the Reds' opponents are at .253 (21st).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 9-10-17 | 5-5-8 | 4-5-9 | 3-2-4 | 6-8-13 | 0-0-0 | 3-5-2 |
| Cubs | 5-7-24 | 4-3-14 | 1-4-10 | 4-3-17 | 1-4-7 | 0-0-0 | 1-3-6 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 11-15-10 | 6-8-4 | 5-7-6 | 4-3-2 | 7-12-8 | 0-0-0 | 4-5-1 |
| Cubs | 18-10-8 | 11-5-5 | 7-5-3 | 13-5-6 | 5-5-2 | 0-0-0 | 6-3-1 |
NRFI/YRFI
The NRFI market is paying -150 and the YRFI is paying +115.
- The NRFI is 16-20 in Reds games this season. The Cubs have a 24-12 NRFI record.
Last Time They Met
The Cubs recorded a 3-2 extra innings victory over the Reds at Wrigley Field yesterday. Michael Busch dominated at the plate in that matchup, notching 1 home run, 2 singles and 2 RBIs. The Cubs have now won three straight at Wrigley Field against the Reds.
