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MLB Prop Bets: Cleveland Guardians vs Minnesota Twins (May 8, 2026)

The Minnesota Twins (16-22) face the Cleveland Guardians (20-19) at Progressive Field on Friday at 7:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Connor Prielipp is the probable pitcher for the Twins, while Parker Messick is the probable pitcher for the Guardians. The Guardians are favored to win at -143, while the Twins are at +119. The total runs line is set at 7.5, with OVER at -115 and UNDER at -105.

  • The Twins (-186) have an 18-20 Run Line record this season, while the Guardians (+153) hold a record of 20-19.
  • The Twins have a 22-13-3 O/U record this season (meaning 22 games have gone over the total runs line, 13 have gone under and three have resulted in a push). The Guardians have a 19-20-0 O/U record.

Scoring Insights

  • The Twins are averaging 4.8 runs per game this season (9th in the league). Comparatively, the Guardians are averaging only 4.2 (21st).
  • In the field, the Twins are allowing a whopping 5.1 runs per game this season (26th in the league), while the Guardians are allowing an average of 4.3 runs (13th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Twins are at .235 (ranking 21st in the Major leagues), while the Guardians are batting .231 (24th).

Home Runs

  • In terms of total home runs this season, the Guardians have hit 39 (T17th in the Major Leagues). Meanwhile, the Twins have managed 43 (T10th).

Runs Batted In

  • Finally, looking at their runs batted in, the Twins have recorded 175 RBIs to rank T7th in the MLB this season. Comparatively, the Guardians have recorded 155 RBIs to rank T18th.

Pitching Insights:

Earned Run Average

  • The Guardians have an earned run average of 4.01 this season (12th in the Majors), while The Twins have an ERA of 4.80 (27th).

Strikeouts

  • Turning our attention to total strikeouts, the Guardians have recorded an impressive 349 this season, ranking 3rd in the MLB. Contrastingly, the Twins rank 26th for total strikeouts, recording only 288.

Opponent Batting Average

  • Opponents are batting an average of .236 against the Guardians this season (11th in the Major Leagues). Comparatively, the Twins' opponents are at .255 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Twins 9-7-22 8-1-11 1-6-11 2-1-4 7-6-18 0-0-0 2-1-7
    Guardians 8-6-25 3-2-11 5-4-14 3-4-11 5-2-14 0-0-0 1-3-6

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Twins 17-12-9 10-4-6 7-8-3 5-1-1 12-11-8 0-0-0 5-1-4
    Guardians 14-13-12 6-4-6 8-9-6 6-4-8 8-9-4 0-0-0 3-4-3

NRFI/YRFI

The NRFI market is paying -150 and the YRFI is paying +115.

  • The NRFI is 22-16 in Twins games this season. The Guardians have a 22-17 NRFI record.

Last Time They Met

The Twins recorded a 6-2 victory over the Guardians at Target Field when these teams last met on September 21, 2025. Brooks Lee was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs. That result snapped the Guardians' four-game winning streak against the Twins at Target Field.