MLB Prop Bets: San Diego Padres vs St. Louis Cardinals (May 8, 2026)
The St. Louis Cardinals (22-15) face the San Diego Padres (22-15) at Petco Park on Friday at 9:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Michael McGreevy is the probable pitcher for the Cardinals, while Griffin Canning is the probable pitcher for the Padres. The Padres are favored to win at -156, while the Cardinals are at +129. The total runs line is set at 8.0, with OVER at -101 and UNDER at -119.
- The Cardinals (-171) have a 24-13 Run Line record this season, while the Padres (+141) hold a record of 18-19.
- The Cardinals have a 19-17-1 O/U record this season (meaning 19 games have gone over the total runs line, 17 have gone under and one has resulted in a push). The Padres have a 16-20-1 O/U record.
Scoring Insights
- The Cardinals are averaging 4.8 runs per game this season (10th in the league). Comparatively, the Padres are averaging 4.4 (16th).
- In the field, the Cardinals are allowing 4.8 runs per game this season (21st in the league), while the Padres are allowing an average of 4.2 runs (T11th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cardinals are at .238 (ranking 18th in the Major leagues), while the Padres are batting .231 (26th).
Home Runs
- In terms of total home runs this season, the Padres have hit 36 (T20th in the Major Leagues). Meanwhile, the Cardinals have managed 45 (T8th).
Runs Batted In
- Finally, looking at their runs batted in, the Cardinals have recorded 172 RBIs to rank 10th in the MLB this season. Comparatively, the Padres have recorded 156 RBIs to rank 17th.
Pitching Insights:
Earned Run Average
- The Padres have an earned run average of 4.15 this season (16th in the Majors), while The Cardinals have an ERA of 4.45 (20th).
Strikeouts
- Turning our attention to total strikeouts, the Cardinals have recorded 258 this season, ranking 30th in the MLB. Meanwhile, the Padres rank 14th for total strikeouts, recording 322.
Opponent Batting Average
- Opponents are batting an average of .237 against the Padres this season (13th in the Major Leagues). Comparatively, the Cardinals' opponents are at .261 (26th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 6-7-24 | 2-3-15 | 4-4-9 | 0-2-1 | 6-5-23 | 0-0-0 | 2-3-5 |
| Padres | 5-6-26 | 4-3-13 | 1-3-11 | 5-3-15 | 0-3-11 | 0-0-2 | 2-2-6 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cardinals | 16-12-9 | 9-5-6 | 7-7-3 | 1-1-1 | 15-11-8 | 0-0-0 | 6-4-0 |
| Padres | 8-18-11 | 6-10-4 | 1-7-7 | 5-10-8 | 3-8-3 | 1-1-0 | 1-7-2 |
NRFI/YRFI
The NRFI market is paying -150 and the YRFI is paying +115.
- The NRFI is 19-18 in Cardinals games this season. The Padres have a 26-11 NRFI record.
Last Time They Met
The Cardinals recorded an upset 2-1 victory over the Padres at Petco Park yesterday. Alec Burleson went yard en route to that victory, hitting a home run to go with an RBI.
