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MLB Prop Bets: Chicago White Sox vs Chicago Cubs (May 15, 2026)

The Chicago Cubs (28-16) face the Chicago White Sox (22-21) at Rate Field on Friday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Edward Cabrera is the probable pitcher for the Cubs, while Sean Burke is the probable pitcher for the White Sox. The Cubs are favored to win at -155, while the White Sox are at +128. The total runs line is set at 8.5, with OVER at -102 and UNDER at -118.

  • The Cubs (+114) have a 21-23 Run Line record this season, while the White Sox (-137) hold a record of 23-20.
  • The Cubs have a 23-19-2 O/U record this season (meaning 23 games have gone over the total runs line, 19 have gone under and two have resulted in a push). The White Sox have a 24-19-0 O/U record.

Scoring Insights

  • The Cubs are averaging 5.0 runs per game this season (T5th in the league). Comparatively, the White Sox are averaging 4.4 (13th).
  • In the field, the Cubs are allowing 4.0 runs per game this season (8th in the league), while the White Sox are allowing an average of 4.6 runs (T20th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cubs are at .244 (ranking 10th in the Major leagues), while the White Sox are batting .233 (22nd).

Home Runs

  • In terms of total home runs this season, the White Sox have hit 56 (5th in the Major Leagues). Meanwhile, the Cubs have managed 53 (T7th).

Runs Batted In

  • Finally, looking at their runs batted in, the Cubs have recorded 203 RBIs to rank 6th in the MLB this season. Comparatively, the White Sox have recorded 179 RBIs to rank T15th.

Pitching Insights:

Earned Run Average

  • The White Sox have an earned run average of 4.22 this season (18th in the Majors), while The Cubs have an ERA of 3.77 (10th).

Strikeouts

  • Turning our attention to total strikeouts, the Cubs have recorded 362 this season, ranking 19th in the MLB. Meanwhile, the White Sox rank T22nd for total strikeouts, recording 342.

Opponent Batting Average

  • Opponents are batting an average of .240 against the White Sox this season (14th in the Major Leagues). Comparatively, the Cubs' opponents are at .229 (9th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cubs 7-7-30 5-3-15 2-4-15 6-3-20 1-4-10 0-0-0 2-1-7
    White Sox 13-8-22 6-4-11 7-4-11 0-1-5 13-7-17 0-0-0 4-2-4

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cubs 21-12-11 13-5-5 8-7-6 16-6-7 5-6-4 0-0-0 3-4-3
    White Sox 20-13-10 10-6-5 10-7-5 0-3-3 20-10-7 0-0-0 5-3-2

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -105.

  • The NRFI is 30-14 in Cubs games this season. The White Sox have a 21-22 NRFI record.

Last Time They Met

The Cubs recorded a 5-4 victory over the White Sox at Rate Field when these teams last met on July 27, 2025. Andrew Benintendi was crushing the ball in that matchup, hitting 2 home runs and recording 4 RBIs.