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MLB Prop Bets: Los Angeles Angels vs Athletics (May 21, 2026)

The Athletics (25-24) face the Los Angeles Angels (17-33) at Angel Stadium of Anaheim on Thursday at 9:38pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Luis Severino is the probable pitcher for the Athletics, while Jose Soriano is the probable pitcher for the Angels. The Angels are favored to win at -112, while the Athletics are at -107. The total runs line is set at 8.0, with OVER at -115 and UNDER at -105.

  • The Athletics (+147) have a 27-22 Run Line record this season, while the Angels (-178) hold a record of 23-27.
  • The Athletics have a 23-23-3 O/U record this season (meaning 23 games have gone over the total runs line, 23 have gone under and three have resulted in a push). The Angels have a 24-26-0 O/U record.

Scoring Insights

  • The Athletics are averaging 4.5 runs per game this season (12th in the league). Comparatively, the Angels are averaging only 4.0 (25th).
  • In the field, the Athletics are allowing 4.6 runs per game this season (19th in the league), while the Angels are allowing an average of 5.3 runs (27th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Athletics are at an impressive .251 (ranking 5th in the Major leagues), while the Angels are batting an underwhelming .224 (29th).

Home Runs

  • In terms of total home runs this season, the Angels have hit 57 (11th in the Major Leagues). Meanwhile, the Athletics have managed 54 (T14th).

Runs Batted In

  • Finally, looking at their runs batted in, the Athletics have recorded 217 RBIs to rank T9th in the MLB this season. Comparatively, the Angels have recorded 192 RBIs to rank T24th.

Pitching Insights:

Earned Run Average

  • The Angels have an earned run average of 4.99 this season (27th in the Majors), while The Athletics have an ERA of 4.32 (22nd).

Strikeouts

  • Turning our attention to total strikeouts, the Athletics have recorded 384 this season, ranking 25th in the MLB. Meanwhile, the Angels rank T12th for total strikeouts, recording 426.

Opponent Batting Average

  • Opponents are batting an average of .243 against the Angels this season (18th in the Major Leagues). Comparatively, the Athletics' opponents are at .254 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 10-14-25 4-8-10 6-6-15 3-6-7 7-8-18 0-0-0 1-2-7
    Angels 12-9-29 7-3-14 5-6-15 2-1-6 10-8-23 0-0-0 0-3-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 21-17-11 8-9-5 13-8-6 4-8-4 17-9-7 0-0-0 3-4-3
    Angels 15-19-16 8-5-11 7-14-5 4-4-1 11-15-15 0-0-0 1-7-2

NRFI/YRFI

The NRFI market is paying -140 and the YRFI is paying +110.

  • The NRFI is 23-26 in Athletics games this season. The Angels have a 25-25 NRFI record.

Last Time They Met

The Athletics recorded a 6-5 extra innings victory over the Angels at Angel Stadium of Anaheim yesterday. Jo Adell was unstoppable in that matchup, hitting a home run, a double and recording an RBI.