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MLB Prop Bets: Chicago Cubs vs San Francisco Giants (June 5, 2026)

The San Francisco Giants (25-38) face the Chicago Cubs (33-30) at Wrigley Field on Friday at 2:20pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Robbie Ray is the probable pitcher for the Giants, while Edward Cabrera is the probable pitcher for the Cubs. The Cubs are favored to win at -163, while the Giants are at +135. The total runs line is set at 11.0, with OVER at -110 and UNDER at -110.

  • The Giants (-137) have a 28-35 Run Line record this season, while the Cubs (+114) hold a record of 25-38.
  • The Giants have a 31-28-4 O/U record this season (meaning 31 games have gone over the total runs line, 28 have gone under and four have resulted in a push). The Cubs have a 34-27-2 O/U record.

Scoring Insights

  • The Giants are averaging 4.0 runs per game this season (26th in the league). Comparatively, the Cubs are averaging +0.7 more at 4.7 runs (8th).
  • In the field, the Giants are allowing 5.0 runs per game this season (23rd in the league), while the Cubs are allowing an average of 4.4 runs (15th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Giants are at .256 (ranking 4th in the Major leagues), while the Cubs are batting .240 (18th).

Home Runs

  • In terms of total home runs this season, the Cubs have hit 71 (12th in the Major Leagues). Meanwhile, the Giants have managed 58 (25th).

Runs Batted In

  • Finally, looking at their runs batted in, the Giants have recorded 243 RBIs to rank 23rd in the MLB this season. Comparatively, the Cubs have recorded 273 RBIs to rank 11th.

Pitching Insights:

Earned Run Average

  • The Cubs have an earned run average of 4.17 this season (18th in the Majors), while The Giants have an ERA of 4.58 (23rd).

Strikeouts

  • Turning our attention to total strikeouts, the Giants have recorded 493 this season, ranking 25th in the MLB. Meanwhile, the Cubs rank 21st for total strikeouts, recording 498.

Opponent Batting Average

  • Opponents are batting an average of .238 against the Cubs this season (13th in the Major Leagues). Comparatively, the Giants' opponents are at .253 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Giants 13-14-36 7-3-18 6-11-18 5-4-12 8-10-24 0-0-0 3-2-5
    Cubs 11-13-39 6-6-20 5-7-19 9-5-28 2-8-11 0-0-0 2-3-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Giants 20-29-14 8-12-8 12-17-6 5-10-6 15-19-8 0-0-0 3-5-2
    Cubs 25-21-17 15-10-7 10-11-10 20-11-11 5-10-6 0-0-0 2-3-5

NRFI/YRFI

The NRFI market is paying +120 and the YRFI is paying -155.

  • The NRFI is 35-28 in Giants games this season. The Cubs have a 38-25 NRFI record.

Last Time They Met

The Giants recorded a 4-3 victory over the Cubs at Oracle Park when these teams last met on August 28, 2025. Willy Adames was crushing the ball in that matchup, hitting 2 home runs and recording 3 RBIs. The Giants have now won five straight against the Cubs.