home team icon
away team icon

MLB Prop Bets: Los Angeles Angels vs St. Louis Cardinals (July 21, 2026)

The St. Louis Cardinals (51-48) face the Los Angeles Angels (40-61) at Angel Stadium of Anaheim on Tuesday at 9:38pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Matthew Liberatore is the probable pitcher for the Cardinals, while Walbert Ureña is the probable pitcher for the Angels. The Cardinals are favored to win at -114, while the Angels are at -105. The total runs line is set at 9.0, with OVER at -105 and UNDER at -114.

  • The Cardinals (+139) have a 57-42 Run Line record this season, while the Angels (-168) hold a record of 50-51.
  • The Cardinals have a 41-54-4 O/U record this season (meaning 41 games have gone over the total runs line, 54 have gone under and four have resulted in a push). The Angels have a 46-54-1 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.5 runs per game this season (13th in the league). Comparatively, the Angels are averaging 4.3 (19th).
  • In the field, the Cardinals are allowing 4.5 runs per game this season (13th in the league), while the Angels are allowing an average of 4.9 runs (24th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .242 (ranking 17th in the Major leagues), while the Angels are batting .239 (20th).

Home Runs

  • In terms of total home runs this season, the Angels have hit 111 (20th in the Major Leagues). Meanwhile, the Cardinals have managed 109 (21st).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 434 RBIs to rank 14th in the MLB this season. Comparatively, the Angels have recorded 421 RBIs to rank 17th.

Pitching Insights:

Earned Run Average

  • The Angels have an earned run average of 4.60 this season (23rd in the Majors), while The Cardinals have an ERA of 4.15 (13th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 745 this season, ranking 28th in the MLB. Meanwhile, the Angels rank 9th for total strikeouts, recording 887.

Opponent Batting Average

  • Opponents are batting an average of .237 against the Angels this season (9th in the Major Leagues). Comparatively, the Cardinals' opponents are at .251 (22nd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 21-17-61 9-8-35 12-9-26 8-6-15 13-11-46 0-0-0 4-0-6
    Angels 27-22-52 17-8-25 10-14-27 5-2-13 22-20-39 0-0-0 3-4-3

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 43-28-28 22-13-17 21-15-11 15-7-7 28-21-21 0-0-0 4-3-3
    Angels 34-41-26 20-15-15 14-26-11 10-8-2 24-33-24 0-0-0 2-6-2

NRFI/YRFI

The NRFI market is paying -120 and the YRFI is paying -110.

  • The NRFI is 53-46 in Cardinals games this season. The Angels have a 47-54 NRFI record.

Last Time They Met

The Angels recorded a 3-2 victory over the Cardinals at Angel Stadium of Anaheim yesterday. Jo Adell was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs.