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MLB Prop Bets: Chicago Cubs vs St. Louis Cardinals (August 14, 2026)

The St. Louis Cardinals (61-60) face the Chicago Cubs (71-51) at Wrigley Field on Friday at 2:20pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Matthew Liberatore is the probable pitcher for the Cardinals, while Clay Holmes is the probable pitcher for the Cubs. The Cubs are favored to win at -182, while the Cardinals are at +169. The total runs line is set at 8.0, with OVER at -109 and UNDER at -110.

  • The Cardinals (-142) have a 66-55 Run Line record this season, while the Cubs (+118) hold a record of 61-61.
  • The Cardinals have a 48-68-5 O/U record this season (meaning 48 games have gone over the total runs line, 68 have gone under and five have resulted in a push). The Cubs have a 64-55-3 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.4 runs per game this season (19th in the league). Comparatively, the Cubs are averaging +0.8 more at 5.2 runs (2nd).
  • In the field, the Cardinals are allowing 4.4 runs per game this season (13th in the league), while the Cubs are allowing an average of 4.3 runs (12th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .241 (ranking 20th in the Major leagues), while the Cubs are batting .249 (8th).

Home Runs

  • In terms of total home runs this season, the Cubs have hit 155 (8th in the Major Leagues). Meanwhile, the Cardinals have managed 122 (T24th).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 516 RBIs to rank 17th in the MLB this season. Comparatively, the Cubs have recorded 597 RBIs to rank 2nd.

Pitching Insights:

Earned Run Average

  • The Cubs have an earned run average of 4.10 this season (15th in the Majors), while The Cardinals have an ERA of 4.07 (12th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 923 this season, ranking 26th in the MLB. Meanwhile, the Cubs rank 24th for total strikeouts, recording 937.

Opponent Batting Average

  • Opponents are batting an average of .246 against the Cubs this season (18th in the Major Leagues). Comparatively, the Cardinals' opponents are at .253 (25th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 25-20-76 12-10-44 13-10-32 10-7-21 15-13-55 0-0-0 2-0-8
    Cubs 27-24-71 17-12-30 10-12-41 24-13-46 3-11-25 0-0-0 1-5-4

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 52-35-34 29-17-20 23-18-14 20-9-9 32-26-25 0-0-0 5-3-2
    Cubs 46-41-35 29-18-12 17-23-23 39-24-20 7-17-15 0-0-0 4-4-2

NRFI/YRFI

The NRFI market is paying -125 and the YRFI is paying -105.

  • The NRFI is 67-54 in Cardinals games this season. The Cubs have a 68-54 NRFI record.

Last Time They Met

The Cubs recorded a 4-2 extra innings victory over the Cardinals at Busch Stadium when these teams last met on July 30. JJ Wetherholt was unstoppable in that matchup, hitting a home run, a single and recording an RBI.