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MLB Prop Bets: Houston Astros vs Athletics (August 21, 2026)

The Athletics (49-79) face the Houston Astros (64-64) at Daikin Park on Friday at 8:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. J.T. Ginn is the probable pitcher for the Athletics, while Hayden Wesneski is the probable pitcher for the Astros. The Astros are favored to win at -194, while the Athletics are at +159. The total runs line is set at 8.0, with OVER at -119 and UNDER at -101.

  • The Athletics (-135) have a 58-70 Run Line record this season, while the Astros (+112) hold a record of 64-64.
  • The Athletics have a 63-60-5 O/U record this season (meaning 63 games have gone over the total runs line, 60 have gone under and five have resulted in a push). The Astros have a 67-54-7 O/U record.

Scoring Insights

  • The Athletics are averaging 4.4 runs per game this season (20th in the league). Comparatively, the Astros are averaging 4.6 (11th).
  • In the field, the Athletics are allowing a whopping 5.8 runs per game this season (30th in the league), while the Astros are allowing an average of 4.9 runs (25th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Athletics are at .244 (ranking 15th in the Major leagues), while the Astros are batting .242 (18th).

Home Runs

  • In terms of total home runs this season, the Astros have hit 170 (3rd in the Major Leagues). Meanwhile, the Athletics have managed 153 (13th).

Runs Batted In

  • Finally, looking at their runs batted in, the Athletics have recorded 533 RBIs to rank 20th in the MLB this season. Comparatively, the Astros have recorded 554 RBIs to rank T12th.

Pitching Insights:

Earned Run Average

  • The Astros have an earned run average of 4.66 this season (26th in the Majors), while The Athletics have an ERA of 5.51 (29th).

Strikeouts

  • Turning our attention to total strikeouts, the Athletics have recorded 1071 this season, ranking 16th in the MLB. Meanwhile, the Astros rank 9th for total strikeouts, recording 1116.

Opponent Batting Average

  • Opponents are batting an average of .240 against the Astros this season (14th in the Major Leagues). Comparatively, the Athletics' opponents are at .271 (29th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 28-38-62 16-19-28 12-19-34 8-10-17 20-28-45 0-0-0 4-3-3
    Astros 36-34-58 20-14-31 16-20-27 15-14-26 21-20-32 0-0-0 3-3-4

Lead After Three Innings

The Athletics are +124 to lead after three innings, while the Astros are -160.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Athletics 46-52-30 26-26-11 20-26-19 11-16-8 35-36-22 0-0-0 5-4-1
    Astros 45-54-29 27-25-13 18-29-16 20-25-10 25-29-19 0-0-0 4-5-1

NRFI/YRFI

The NRFI market is paying -110 and the YRFI is paying -115.

  • The NRFI is 58-70 in Athletics games this season. The Astros have a 55-73 NRFI record.

Last Time They Met

The Athletics recorded a 5-0 victory over the Astros at Daikin Park when these teams last met on June 7. Brent Rooker was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs.